Compile Data Set for Download or QSAR
Report error Found 245 of affinity data for UniProtKB/TrEMBL: P80192
LigandPNGBDBM24945(20-hydroxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24946(3-(2-hydroxyethyl)-3,13-diazahexacyclo[14.8.0.0^{2...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24950(20-hydroxy-3-(2-hydroxyethyl)-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24951(20-(cyclopropylmethoxy)-3-(2-hydroxyethyl)-3,13-di...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24953(20-(cyclohexyloxy)-3-(2-hydroxyethyl)-3,13-diazahe...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24954(3-(2-hydroxyethyl)-20-(pyridin-2-ylmethoxy)-3,13-d...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24955(3-(2-hydroxyethyl)-20-(2-methoxyethoxy)-3,13-diaza...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24956(20-[2-(benzyloxy)ethoxy]-3-(2-hydroxyethyl)-3,13-d...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24957(20-(2-hydroxyethoxy)-3-(2-hydroxyethyl)-3,13-diaza...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24958(2-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM24959(4-{[3-(2-hydroxyethyl)-14-oxo-3,13-diazahexacyclo[...)
Affinity DatapH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
LigandPNGBDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  9.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM31099(CHEMBL45741 | Flavopiridol | cid_24867231 | 2-(2-c...)
Affinity DataKd:  5.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd:  290nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  3.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  1.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  15nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  2.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  3.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  390nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  15nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  3.5nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  10nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  15nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  220nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  10nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  15nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
LigandPNGBDBM13535(N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd:  15nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  5.70E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM17055((9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydr...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  3.20E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  2.70E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM15244(cid_3038525 | 5-(2,6-dichlorophenyl)-2-[(2,4-diflu...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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