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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190540(US9181184, 27)
Affinity DataEC50:  1.73E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataEC50:  9.88E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | alp...)
Affinity DataEC50:  2.81E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18364(CN-DNJ | (2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-nony...)
Affinity DataEC50:  7.00E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190539(US9181184, 26)
Affinity DataEC50:  6.60E+3nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190538(US9181184, 25)
Affinity DataEC50:  6.65E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190537(US9181184, 24)
Affinity DataEC50:  7.71E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190536(US9181184, 23)
Affinity DataEC50:  1.21E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190535(US9181184, 21)
Affinity DataEC50:  2.10E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
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TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190533(US9181184, 19)
Affinity DataEC50:  3.72E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataEC50:  7.45E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataEC50:  1.18E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190528(US9181184, 11)
Affinity DataEC50:  4.77E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190529(US9181184, 15)
Affinity DataEC50:  5.84E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190530(US9181184, 16)
Affinity DataEC50:  6.97E+4nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)
Affinity DataEC50:  6.53E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190531(US9181184, 17 | US9181184, 18)
Affinity DataEC50:  1.04E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM190534(US9181184, 20)
Affinity DataEC50:  4.68E+5nMpH: 4.0Assay Description:Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
Go to US Patent

TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335390(N-Hexoxypentyl-1-deoxynojirimycin | CHEMBL1651630)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335389(N-Heptoxypentyl-1-deoxynojirimycin | CHEMBL1651631)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335392(N-Butoxypentyl-1-deoxynojirimycin | CHEMBL1651628)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335388(N-Octoxypentyl-1-deoxynojirimycin | CHEMBL1651632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335399(N-Pentyl-1-deoxynojirimycin | CHEMBL1651549)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 1.36E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401967(CHEMBL2207959)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401973(CHEMBL2207953)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401970(CHEMBL2207956)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401968(CHEMBL2207958)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401972(CHEMBL2207954)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401971(CHEMBL2207955)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401975(CHEMBL2207951)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401974(CHEMBL2207952)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401978(CHEMBL2207949)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401979(CHEMBL2207948)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401969(CHEMBL2207957)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401977(CHEMBL2207950)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50401976(CHEMBL2203334)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM243075(α-Gl inhibitor, C3)
Affinity DataIC50: 6.41E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25°C with minor changes, according to the meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of liver glucosidase in Swiss mouse liver extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335394(N-Octyl-L-ido-1-deoxynojirimycin | CHEMBL1651626)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335385(N-Pentoxypentyl-L-ido-1-deoxynojirimycin | CHEMBL1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
Amicus Therapeutics

US Patent
LigandPNGBDBM50335393(N-Nonyl-L-ido-1-deoxynojirimycin | CHEMBL1651627)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
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