Compile Data Set for Download or QSAR
Report error Found 223 for UniProtKB: P68403
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3045(3-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...)
Affinity DataIC50: 2nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C alpha/beta/gamma type(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.70nMAssay Description:In vitro inhibition of [32P] incorporation into histones by rat brain partially purified Protein kinase C in the presence of PMA, [Ca2+] and phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50108296(Indolocarbazole analogue | CHEMBL289772)
Affinity DataIC50: 3nMAssay Description:Inhibition of protein kinase C (PKC) from rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3049(23-[3-(dimethylamino)-2-hydroxypropyl]-7-methoxy-3...)
Affinity DataIC50: 4nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2714(3-[(2S)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 4.10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3047(4-{19-methoxy-23-methyl-12,14-dioxo-3,13,23-triaza...)
Affinity DataIC50: 5nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3046(3-{7,19-dimethoxy-23-methyl-12,14-dioxo-3,13,23-tr...)
Affinity DataIC50: 6nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM50282632(Ro-32-0557 | 3-((3aR,10aR)-2-Methyl-2,3,3a,4,10,10...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Protein kinase C betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2700(3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]...)
Affinity DataIC50: 7.60nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3035(3-{7,19-dihydroxy-23-methyl-14-oxo-3,13,23-triazah...)
Affinity DataIC50: 9nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 9nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2712(3-(1-methyl-1H-indol-3-yl)-4-{2-[(methylamino)meth...)
Affinity DataIC50: 9.80nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2715(3-[(2R)-2-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]i...)
Affinity DataIC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2699(3-[2-(aminomethyl)-1H,2H,3H-benzo[b]pyrrolizin-9-y...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2702(3-[3-(aminomethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol-...)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3038(23-[3-(dimethylamino)propyl]-7,19-dihydroxy-3,13,2...)
Affinity DataIC50: 16nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3044(3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazah...)
Affinity DataIC50: 16nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2704(3-[8-(aminomethyl)-6H,7H,8H,9H,10H-azepino[1,2-a]i...)
Affinity DataIC50: 16.5nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
Affinity DataIC50: 19nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3033(Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...)
Affinity DataIC50: 20nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

LigandPNGBDBM3033(Indolocarbazole deriv. | 3-{23-methyl-14-oxo-3,13,...)
Affinity DataIC50: 20nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3048(23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...)
Affinity DataIC50: 21nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2703(3-[3-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM50280871(12-(3-azidopropyl)-13-methyl-6,7,12,13-tetrahydro-...)
Affinity DataIC50: 25nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3178(3-(1-Methyl-3-indolyl)-4-[1-[3-(2-nitroguanidino)p...)
Affinity DataIC50: 26nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
LigandPNGBDBM50280873(2-(13-ethyl-5-oxo-6,7,12,13-tetrahydro-5H-indolo[2...)
Affinity DataIC50: 27nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3176([(4-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 28nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3041(Indolocarbazole deriv. | 23-[3-(dimethylamino)-2-h...)
Affinity DataIC50: 30nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)
Affinity DataIC50: 30.5nMAssay Description:Inhibition of Protein kinase C betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3180(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 31nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3040(23-(3-aminopropyl)-3-methyl-3,13,23-triazahexacycl...)
Affinity DataIC50: 32nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

LigandPNGBDBM50280870(12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahy...)
Affinity DataIC50: 32nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3171(3-[1-[3-(Methylamino)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3043(3-{23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[1...)
Affinity DataIC50: 38nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3174([(2-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 41nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2705(3-[8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyr...)
Affinity DataIC50: 42nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3039(23-[3-(dimethylamino)propyl]-3-methyl-3,13,23-tria...)
Affinity DataIC50: 45nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 45nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2701(3-[2-(2-aminoethyl)-1H,2H,3H,4H-pyrido[1,2-a]indol...)
Affinity DataIC50: 47nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3177([(5-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-d...)
Affinity DataIC50: 47nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2713(3-[6,7,8,9-Tetrahydro-8-[(trimethylamino)methyl]py...)
Affinity DataIC50: 49nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2005
Entry Details Article
PubMed
TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM3034(3-{7,19-dimethoxy-23-methyl-14-oxo-3,13,23-triazah...)
Affinity DataIC50: 56nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

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