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Report error Found 18 of affinity data for UniProtKB/TrEMBL: P55926
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50609260(CHEMBL5274562)
Affinity DataEC50:  1.20E+3nMAssay Description:Modulation of rat ASIC1 by two electrode voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50157090(6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ASIC1a in rat dorsal root ganglion neurons assessed as reduction in peak current preincubated for 120 secs followed by acid medium stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of ASIC1 in Sprague-Dawley rat articular chondrocytes assessed as decrease in acid-induced intracellular calcium level by Fluo-3AM dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.4 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.9 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50250133(Butibufen)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.7 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.7 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50250130(CHEMBL4083814)
Affinity DataIC50: 4.17E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 5.13E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.4 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 5.13E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes at pH 6.4 by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50250132(CHEMBL4080879)
Affinity DataIC50: 9.55E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50250131(CHEMBL190275)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Rwth Aachen University

Curated by ChEMBL
LigandPNGBDBM50295285(Ibufenac | (4-Isobutyl-phenyl)-acetic acid | 2-(4-...)
Affinity DataIC50: 1.02E+6nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2019
Entry Details Article
PubMed