Compile Data Set for Download or QSAR
Report error Found 539 of affinity data for UniProtKB/TrEMBL: P55085
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329483(2-Furoyl-Cha-Ile-NH2 | CHEMBL1271235)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329484(2-Pyrazoyl-Cha-Ile-NH2 | CHEMBL1270927)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329485(5-Isoxazoyl-Cha-Ile-NH2 | CHEMBL1270823)
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329486(4-(2-Methyloxazoyl)-Cha-Ile-NH2 | CHEMBL1271236)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329488(5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[am...)
Affinity DataEC50:  251nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329489(5-Isoxazoyl-Cha-Ile-(piperidin-3-yl)-(4-[aminometh...)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329490(5-Isoxazoyl-Cha-Ile-(4-aminophenyl)-(4-[aminomethy...)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329491(5-Isoxazoyl-Cha-Ile-4-aminophenyl-(4-[aminomethyl]...)
Affinity DataEC50:  316nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329492(5-Isoxazoyl-Cha-Ile-(4-[aminomethyl]phenyl)-(4-[am...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329493(5-Isoxazoyl-Cha-Ile-(piperidin-4-yl)-(4-[aminometh...)
Affinity DataEC50:  1.71E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329494(5-isoxazoyl-Cha-Ile-(3-aminophenyl)-(4-[aminomethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329495(5-Isoxazoyl-Cha-Ile-(piperidin-2-yl)-(4-[aminometh...)
Affinity DataEC50:  7.94E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329496(5-Isoxazoyl-Cha-Ile-(3R,6S)-6-amino-3-(4-[aminomet...)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329497(5-Isoxazoyl-Cha-Ile-(R)-3-amino-1-([S]-1-[4-(amino...)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  142nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339245(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  311nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  138nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  1.77E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339245(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339247(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339248(4-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  6.59E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  840nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440863(CHEMBL2431716)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation incubated for 10 mins measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50203290(CHEMBL3896632)
Affinity DataEC50:  700nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium release incubated for 30 mins measured for 60 secs by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50203294(CHEMBL3947297)
Affinity DataEC50:  700nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium release incubated for 30 mins measured for 60 secs by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440863(CHEMBL2431716)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation incubated for 10 mins measured after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50203297(CHEMBL3956750)
Affinity DataEC50:  700nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium release incubated for 30 mins measured for 60 secs by Flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440850(CHEMBL238396)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440851(CHEMBL267729)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440852(CHEMBL414319)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440853(CHEMBL236037)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440854(CHEMBL236292)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440855(CHEMBL236293)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440856(CHEMBL398128)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440857(CHEMBL392253)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440859(CHEMBL2431718)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at PAR2 in human platelets by platelet aggregation assay in presence of SFLLRNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440860(CHEMBL2431720)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human PAR2 expressed in African green monkey COS7 cells assessed as stimulation of inositol triphosphate productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as increase in intracellular calcium level by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412717(AC-55541 | CHEMBL493076)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as increase in intracellular calcium level by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of phosphatidylinositol hydrolysis after 45 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412717(AC-55541 | CHEMBL493076)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of phosphatidylinositol hydrolysis after 45 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412708(AC-264613 | CHEMBL494502)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of cell proliferation after 5 days by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50412717(AC-55541 | CHEMBL493076)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of cell proliferation after 5 days by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440872(CHEMBL2431724)
Affinity DataEC50:  10nMAssay Description:Agonist activity at PAR2 in human 16HBE14o- cells assessed as increase in MAPK levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440872(CHEMBL2431724)
Affinity DataEC50:  4nMAssay Description:Agonist activity at PAR2 in human 16HBE14o- cells assessed as increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440873(CHEMBL2431723)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440874(CHEMBL398131)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440875(CHEMBL236704)
Affinity DataEC50:  300nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440876(CHEMBL396183)
Affinity DataEC50:  400nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440877(CHEMBL397820)
Affinity DataEC50:  400nMAssay Description:Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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