Compile Data Set for Download or QSAR
Report error Found 7 of affinity data for UniProtKB/TrEMBL: P54827
LigandPNGBDBM14397(5-(5-acetyl-2-ethoxyphenyl)-1-methyl-3-propyl-1H,6...)
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14396(5-{2-ethoxy-5-[2-(morpholin-4-yl)acetyl]phenyl}-1-...)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14394(5-(5-Acetyl-2-butoxy-3-pyridinyl)-3-ethyl-2-(2-pyr...)
Affinity DataIC50: 183nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14392(3-ethyl-5-{5-[(4-ethylpiperazine-1-)sulfonyl]-2-(2...)
Affinity DataIC50: 386nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14393(5-(2-butoxy-5-acetylpyridin-3-yl)-3-ethyl-2-(1-eth...)
Affinity DataIC50: 840nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
LigandPNGBDBM14395(5-[2-Butoxy-5-(1-hydroxyethyl)-3-pyridinyl]-3-ethy...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed