Compile Data Set for Download or QSAR
Report error Found 14 of affinity data for UniProtKB/TrEMBL: P53792
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataEC50:  3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 1.15nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50344685(4-((5-(2,3-dihydro-1H-inden-2-yl)-4-propyl-4H-1,2,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50344681(6,8-dimethyl-4-((4-propyl-5-(pyridin-2-yl)-4H-1,2,...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50467750(CHEMBL4279519)
Affinity DataIC50: 16nMAssay Description:Inhibition of rat SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 96nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50340014(4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50426887(CHEMBL2323695)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50426888(CHEMBL2323694)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394534(CHEMBL2159102)
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394532(CHEMBL2159094)
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394531(CHEMBL2159091)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed