Compile Data Set for Download or QSAR
Report error Found 6 of affinity data for UniProtKB/TrEMBL: P51657
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515434(CHEMBL4518587)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126972(CHEMBL3629586)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126973(CHEMBL3629587)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515436(CHEMBL4441313)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515435(CHEMBL4513439)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515432(CHEMBL4447938)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed