Compile Data Set for Download or QSAR
Report error Found 1309 of affinity data for UniProtKB/TrEMBL: P50579
LigandPNGBDBM17451(5-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DatapH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
LigandPNGBDBM50433373(CHEMBL2375609)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433374(CHEMBL2375610)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433378(CHEMBL2375629)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM47468(N-(2-phenylethyl)-2-(2-pyridinyl)-4-quinazolinamin...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433379(CHEMBL2375611)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433380(CHEMBL2375612)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433381(CHEMBL2375613)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433382(CHEMBL1329554)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433383(CHEMBL2375614)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433384(CHEMBL45721)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433385(CHEMBL49678)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433386(CHEMBL2375615)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433387(CHEMBL2375616)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433388(CHEMBL2375617)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433389(CHEMBL2375618)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433390(CHEMBL2375619)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433391(CHEMBL2375620)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433392(CHEMBL2375621)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433393(CHEMBL2375622)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433394(CHEMBL2375623)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433395(CHEMBL2375624)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433396(CHEMBL2375625)
Affinity DataEC50: >2.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433397(CHEMBL2375626)
Affinity DataEC50: >2.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433398(CHEMBL2375607)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433399(CHEMBL2375608)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human methionine aminopeptidase 2 in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM401307(US10005756, Compound A78)
Affinity DataKd:  0.880nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM401307(US10005756, Compound A78)
Affinity DataKd:  0.880nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50531163(CHEMBL4464946)
Affinity DataKd:  2.10nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50531161(CHEMBL4448724)
Affinity DataKd:  1.10nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50531163(CHEMBL4464946)
Affinity DataKd:  2.10nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50531161(CHEMBL4448724)
Affinity DataKd:  1.10nMAssay Description:Inhibition of 5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide-Dy647 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM36597(FOS-69)
Affinity DataIC50: 0.100nMpH: 7.35 T: 2°CAssay Description:Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
LigandPNGBDBM50137405(Carbamic acid (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2...)
Affinity DataIC50: 0.390nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM36589(Ovalicin)
Affinity DataIC50: 0.400nMpH: 7.35 T: 2°CAssay Description:Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
LigandPNGBDBM50295172(4-Hydroxy-5-methoxy-4-[(2S,3R)-2-methyl-3-(3-methy...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50137403(Acetyl-carbamic acid (3R,4S,5S,6R)-5-methoxy-4-[(R...)
Affinity DataIC50: 0.430nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50137404(Acetic acid (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-m...)
Affinity DataIC50: 0.510nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50113436(fumagillin | CHEMBL32838)
Affinity DataIC50: 0.630nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50137402(4-Ethyl-piperazine-1-carboxylic acid (3R,4S,5S,6R)...)
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50512383(CHEMBL137766)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM36588(AGM-1470)
Affinity DataIC50: 1nMpH: 7.35 T: 2°CAssay Description:Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
LigandPNGBDBM50131562(Deca-2,4,6,8-tetraenedioic acid mono-{5-methoxy-4-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against purified recombinant human Methionine Aminopeptidase 2 (MetAP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM17446((3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50137406(Acetic acid (3R,4S,5S,6R)-4-{1-[(E)-benzyloxyimino...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50137408(Carbamic acid (3R,4S,5S,6R)-4-{1-[(E)-benzyloxyimi...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM188704(US9169246, 246)
Affinity DataIC50: 1.46nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

LigandPNGBDBM50137409(Carbamic acid (3R,4S,5S,6R)-4-((E)-1,5-dimethyl-he...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against Methionine aminopeptidase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
LigandPNGBDBM36595(FOS-68)
Affinity DataIC50: 2nMpH: 7.35 T: 2°CAssay Description:Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2011
Entry Details Article
PubMed
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