Compile Data Set for Download or QSAR
Report error Found 1298 of affinity data for UniProtKB/TrEMBL: P47900
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  1.58E+3nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(K280A) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  25nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(T222A) human P2Y1 receptor in presence of MRS2179 (P<0.005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  2.5nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(T221A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  378nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(Q307A) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  10nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(S314T) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  12nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(T221A) human P2Y1 receptor in presence of MRS2179 (P<0.005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  1.90nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(WT) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  1.52E+3nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(K280A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  323nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(Q307A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  1.90nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(S317A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  12nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(S317A) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  12nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(Y136A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  103nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(F131A) human P2Y1 receptor in presence of MRS2179 (P<0.05)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  53nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(H132A) human P2Y1 receptor in presence of MRS2179 (P<0.005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  2.27E+3nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(R310K) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  115nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(H277A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  18nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(H132A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  31nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(S314T) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  13nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(WT) human P2Y1 receptor in presence of MRS2179 (P<0.005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  324nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(R310K) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  19nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(F131A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  20nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(F226A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  11nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(T222A) human P2Y1 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  36nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(Y136A) human P2Y1 receptor in presence of MRS2179 (P<0.005)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  738nMAssay Description:Compound was measured for the antagonism of the activation of phospholipase C in mutant(H277A) human P2Y1 receptor in presence of MRS2179More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  850nMAssay Description:Agonist activity at human P2Y1 receptor expressed in human 1321N1 cells assessed as increase of intracellular calcium level after 30 mins using fura-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM85043(CHEMBL69234 | CAS_149017-66-3 | NSC_6093163 | PPAD...)
Affinity DataEC50:  1.82E+4nMAssay Description:Evaluated for agonist activity against phospholipase C coupled P2Y purinoceptor 1 (P2Y1) of rat erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  880nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  130nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  17nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131060(CHEMBL3634186)
Affinity DataEC50:  90nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131061(CHEMBL3634185)
Affinity DataEC50:  37nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131062(CHEMBL3634184)
Affinity DataEC50:  880nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131063(CHEMBL3634183)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131064(CHEMBL3634182)
Affinity DataEC50:  17nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50131059(CHEMBL575257)
Affinity DataEC50:  130nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118230(5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADEN...)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50368125(ADP | ADENOSINE DIPHOSPHATE)
Affinity DataEC50:  24nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  850nMAssay Description:Agonist activity at GFP-tagged human P2Y1R transfected in human 1321N1 cells assessed as increase in intracellular Ca2+ level by fura 2/AM probe-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50308334(Di-(2-MeS)-adenosine 5',5''-P1,P4,alpha,beta-Methy...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50308335(Di-(2-MeS)-adenosine 5',5''-P1,P4,beta,gamma-Methy...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50308336({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM2(CHEMBL14249 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-pu...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at P2Y1 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM31995(ADP | CHEMBL14830 | Adenosine Diphosphate (ADP))
Affinity DataEC50:  14nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50268012({[({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at G-protein coupled P2Y1 receptor expressed in human 1321N1 cells assessed as increase in calcium by Fura2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50308552((1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-2-chloro-9H-purin...)
Affinity DataEC50:  722nMAssay Description:Activation of human P2Y1 receptor expressed in human 1321N1 cells assessed as induction of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50308552((1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-2-chloro-9H-purin...)
Affinity DataEC50:  1.89nMAssay Description:Agonist activity at human P2Y1 receptor expressed in human 1321N1 cells by PLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
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