Compile Data Set for Download or QSAR
Report error Found 586 for UniProtKB: P47898
LigandPNGBDBM50224303(CHEMBL283686)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50224302(CHEMBL31783)
Affinity DataKd:  43nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50224305(CHEMBL285355)
Affinity DataKd:  8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585906(CHEMBL5077128)
Affinity DataEC50:  355nMAssay Description:Agonist activity at human 5-HT5A receptor transfected in HTLA cells assessed as increase in beta-arrestin 2 recruitment at 10 uM incubated for 18 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50585907(CHEMBL5082447)
Affinity DataEC50:  3.63E+3nMAssay Description:Agonist activity at human 5-HT5A receptor transfected in HTLA cells assessed as increase in beta-arrestin 2 recruitment at 10 uM incubated for 18 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422022(CHEMBL101138)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 106nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422016(CHEMBL323334)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422019(CHEMBL321963)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422021(CHEMBL103549)
Affinity DataIC50: 126nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in HEK293 cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422025(CHEMBL103371)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422029(CHEMBL103388)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422026(CHEMBL320412)
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422023(CHEMBL318571)
Affinity DataIC50: 501nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataIC50: 501nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422024(CHEMBL319223)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422017(CHEMBL103854)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422028(CHEMBL102548)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422020(CHEMBL103205)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422030(CHEMBL102586)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50330813(3-[(1S,3R)-3-Dimethylaminocyclopentyl]-1H-indole-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422018(CHEMBL102645)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50224302(CHEMBL31783)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50330441(3-amino-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)buty...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50422027(CHEMBL2111620)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor from pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50224300(CHEMBL352315)
Affinity DataIC50: 2.24E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...)
Affinity DataIC50: 3.32E+3nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT5A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50026868(2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...)
Affinity DataIC50: 3.32E+3nMAssay Description:Displacement of [3H] LSD from human recombinant 5-HT5A receptor expressed in CHO-K1 cells incubated for 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50105109(4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-c...)
Affinity DataIC50: 3.38E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50105107(1-{4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazin-1...)
Affinity DataIC50: 5.52E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50060429((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for the displacement of [3H]5-HT binding to cloned human 5-hydroxytryptamine 5A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50304075(3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50353901(CHEMBL1829958)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM10838(3-(2-aminopyrimidin-4-yl)-1H-indol-4-ol | Meridian...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50353903(CHEMBL1829961)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50022539(CHEMBL14982)
Affinity DataIC50: 1.55E+4nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50022538(CHEMBL14651)
Affinity DataIC50: 1.82E+4nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50022537(CHEMBL14508)
Affinity DataIC50: 2.75E+4nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50224301(CHEMBL417480)
Affinity DataIC50: 4.07E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50224303(CHEMBL283686)
Affinity DataIC50: 4.08E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50224305(CHEMBL285355)
Affinity DataIC50: 1.51E+5nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
LigandPNGBDBM50022536(CHEMBL15228)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of AA+phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50022536(CHEMBL15228)
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of ADP by the compound in response of SECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
LigandPNGBDBM50022596(CHEMBL14837)
Affinity DataIC50: 4.37E+5nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details Article
PubMed
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