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TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM3149(Acyclic Balanol Analog (-)-1 | 2-{[2,6-dihydroxy-4...)
Affinity DataIC50: 440nMAssay Description:Inhibition of bovine C-terminal truncated GRK5 (561 residues) assessed as decrease in phosphorylation of urea-washed bovine rod outer segments preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50529458(CHEMBL4557065)
Affinity DataIC50: 700nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50173313(CHEMBL1738878)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260141(CHEMBL4097393)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260140(CHEMBL4090144)
Affinity DataIC50: 7.09E+3nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50257350(CHEMBL1738877)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260146(CHEMBL4064274)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260138(CHEMBL4075475)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260148(CHEMBL4070885)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260147(CHEMBL4063014)
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260127(CHEMBL4091281)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260130(CHEMBL4090923)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM14056(N-(7-chloro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(...)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50529472(CHEMBL4578499)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260129(CHEMBL4098656)
Affinity DataIC50: 4.23E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM14052(N-(1H-indazol-5-yl)-2-methyl-4-(naphthalen-2-yl)-6...)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260128(CHEMBL4071638)
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260133(CHEMBL4077197)
Affinity DataIC50: 7.63E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM14051(4-(3,4-Dichlorophenyl)-N-1H-indazol-5-yl-2-methyl-...)
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260125(CHEMBL4099398)
Affinity DataIC50: 8.43E+4nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260126(CHEMBL4073639)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260142(CHEMBL4079362)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50173319(CHEMBL3809020 | US10023564, Example 11)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260154(CHEMBL4077133)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260131(CHEMBL4101136)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260136(CHEMBL4077459)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260144(CHEMBL4081802)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50529465(CHEMBL4464632)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50529461(CHEMBL4536595)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50529464(CHEMBL4543927)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260143(CHEMBL4087244)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260132(CHEMBL4083142)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260134(CHEMBL4072898)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260135(CHEMBL4076131)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260149(CHEMBL4074476)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260137(CHEMBL4062790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260150(CHEMBL4084465)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260139(CHEMBL4075712)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260151(CHEMBL4076529)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50173320(GSK-180736A | GSK180736A | US10023564, Compound GS...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260152(CHEMBL4105100)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50260145(CHEMBL4070290)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50331515(PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK5 (561 residues) assessed as decrease in phosphorylation of tubulin preincubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50331515(PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50331515(PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of C-terminal hexahistidine tagged bovine GRK5 (561 residues) assessed as decrease in phosphorylation of light-activated bovine rod outer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed
TargetG protein-coupled receptor kinase 5(Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50191325(CHEMBL3918278)
Affinity DataIC50: 6.31E+5nMAssay Description:Inhibition of bovine GRK5 assessed as decrease in phosphorylation of tubulin after 5 mins by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2018
Entry Details Article
PubMed