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TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334463(1,3,5-tri-{5-[1-(3-picolinium)]-pent-1-ynyl}benzen...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50445330(CHEMBL3104243)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334472(1,3,5-tris(5-(3,4-dihydroisoquinolin-2(1H)-yl)pent...)
Affinity DataIC50: 0.350nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567433(CHEMBL4869892)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334464(1,12-bis(3-methyl-5,6-dihydropyridin-1(2H)-yl)dode...)
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50445330(CHEMBL3104243)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238606(CHEMBL4099865)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current at -70 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567430(CHEMBL4860756)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567432(CHEMBL4876825)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119774(N,N'-(1,12-dodecandiyl)-bis-pyridinium dibromide |...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at nAChR-alpha-6-beta-2 in Sprague-Dawley rat striatal slices assessed as inhibition of nicotine-evoked [3H]dopamine uptake by li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119774(N,N'-(1,12-dodecandiyl)-bis-pyridinium dibromide |...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334474(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567431(CHEMBL4878931)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567435(CHEMBL4872191)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334466(1,3,5-tris(5-(3-methyl-5,6-dihydropyridin-1(2H)-yl...)
Affinity DataIC50: 3.22nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459664(CHEMBL4218406)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334470(1,12-bis(3,4-dihydroisoquinolin-2(1H)-yl)dodecane ...)
Affinity DataIC50: 8.59nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50547502(CHEMBL4793300)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat alpha6alpha3beta2beta3 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334471(1,10-bis(3,4-dihydroisoquinolin-2(1H)-yl)decane | ...)
Affinity DataIC50: 9.91nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459654(CHEMBL4206157)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50445326(CHEMBL3104239)
Affinity DataIC50: 11nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50516340(CHEMBL4439678)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567426(CHEMBL4878856)
Affinity DataIC50: 15nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50516340(CHEMBL4439678)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50516316(CHEMBL4454928)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459656(CHEMBL4214931)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459653(CHEMBL4211045)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567413(CHEMBL4865365)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459661(CHEMBL4215453)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567426(CHEMBL4878856)
Affinity DataIC50: 23nMAssay Description:Inhibition of rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567413(CHEMBL4865365)
Affinity DataIC50: 27nMAssay Description:Inhibition of rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandPNGBDBM50445322(CHEMBL3104235)
Affinity DataIC50: 28nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334475(3,3',3'',3'''-(1,1',1'',1'''-(5,5',5'',5'''-(benze...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238616(CHEMBL3104238)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM86240(Gly-L-Cys(1)-L-Cys(2)-L-Ser-L-Asn-L-Pro-L-Val-L-Cy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238610(CHEMBL4062759)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50445331(CHEMBL3104245)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334465(1,10-bis(3-methyl-5,6-dihydropyridin-1(2H)-yl)deca...)
Affinity DataIC50: 37.4nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238589(CHEMBL4061135)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238580(CHEMBL4099451)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119805(1,12-di(2-isoquinoliniumyl)dodecane; with dibromid...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238579(CHEMBL4070842)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567438(CHEMBL4865866)
Affinity DataIC50: 44nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567438(CHEMBL4865866)
Affinity DataIC50: 44nMAssay Description:Inhibition of rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567427(CHEMBL4872474)
Affinity DataIC50: 45nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238607(CHEMBL4069809)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50238611(CHEMBL4097007)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50459660(CHEMBL4206670)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6/beta-4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50516342(CHEMBL4461998)
Affinity DataIC50: 50nMAssay Description:Inhibition of rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-6(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50334469(2,2',2'',2'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
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