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Report error Found 5174 for UniProtKB: P41594
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438276(CHEMBL2408579)
Affinity DataEC50:  694nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in CHO cells assessed as increase of L-quisqualate-induced intracellular cAMP accumulation t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50231741(2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one | CH...)
Affinity DataEC50:  50nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438279(CHEMBL2408410)
Affinity DataEC50:  31nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437099(CHEMBL2403587)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437100(CHEMBL2403580)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437101(CHEMBL2403656)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437102(CHEMBL2403654)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437103(CHEMBL2403653)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437104(CHEMBL2403652)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437105(CHEMBL2403651)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437106(CHEMBL2403650)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437107(CHEMBL2403649)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437108(CHEMBL2403685)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437109(CHEMBL2403682)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437110(CHEMBL2403681)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437111(CHEMBL2403680)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437084(CHEMBL2403679)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437112(CHEMBL2403678)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437113(CHEMBL2403677)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437114(CHEMBL2403676)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437115(CHEMBL2403675)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437116(CHEMBL2403672)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437117(CHEMBL2403671)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437087(CHEMBL2403670)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437118(CHEMBL2403668)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437091(CHEMBL2403665)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437092(CHEMBL2403664)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437093(CHEMBL2403663)
Affinity DataEC50:  5.20E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437095(CHEMBL2403661)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437119(CHEMBL2403648)
Affinity DataEC50:  1.60E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437094(CHEMBL2403662)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437120(CHEMBL2403703)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437072(CHEMBL2403695)
Affinity DataEC50:  790nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437075(CHEMBL2403692)
Affinity DataEC50:  640nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437121(CHEMBL2403701)
Affinity DataEC50:  470nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437122(CHEMBL2403700)
Affinity DataEC50:  320nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437123(CHEMBL2403699)
Affinity DataEC50:  290nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437096(CHEMBL2403660)
Affinity DataEC50:  290nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437124(CHEMBL2403657)
Affinity DataEC50:  250nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437125(CHEMBL2403647)
Affinity DataEC50:  220nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437126(CHEMBL2403697)
Affinity DataEC50:  190nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437071(CHEMBL2403696)
Affinity DataEC50:  167nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437127(CHEMBL2403594)
Affinity DataEC50:  160nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437128(CHEMBL2403655)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437076(CHEMBL2403691)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437073(CHEMBL2403694)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437098(CHEMBL2403658)
Affinity DataEC50:  112nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437086(CHEMBL2403673)
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437129(CHEMBL2403698)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437085(CHEMBL2403674)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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