Affinity DataEC50: 0.0800nMAssay Description:Compound was evaluated for increase in [35S]GTP-gamma-S, binding for human ORL1 receptor carried out in CHO cell membranes; Nd: no dataMore data for this Ligand-Target Pair
Affinity DataEC50: 407nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.270nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.450nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.470nMAssay Description:Affinity for human Opioid receptor like 1 (ORL-1) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 136nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 85nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 82nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 124nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human nociceptin opioid receptor transfected in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding after 60 min...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity measured by GTPgammaS binding against Opioid receptor like 1 in CHO cells.More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity measured by GTPgammaS binding against Opioid receptor like 1 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against nociceptin produced GTPgammaS binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonistic activity against nociceptin produced GTPgammaS binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against nociceptin produced GTPgammaS binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 117nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Concentration required for stimulation of [35S]GTP-gamma-S, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 5.46E+4nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity on nociceptin-induced maximal [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity on nociceptin-induced maximal [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity on nociceptin-induced maximal [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity on nociceptin-induced maximal [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6.90E+3nMAssay Description:Agonistic activity against nociceptin produced GTPgammaS binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as increase in SCH-221510-stimulated [35S]GTPgammaS binding in presence of GDPMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as increase in SCH-221510-stimulated [35S]GTPgammaS binding in presence of GDPMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as increase in SCH-221510-stimulated [35S]GTPgammaS binding in presence of GDPMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as increase in SCH-221510-stimulated [35S]GTPgammaS binding in presence of GDPMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 269nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 8.10nMAssay Description:Partial agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillatio...More data for this Ligand-Target Pair
Affinity DataEC50: 116nMAssay Description:Partial agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillatio...More data for this Ligand-Target Pair
Affinity DataEC50: 29.7nMAssay Description:Efficacy for human ORL1 receptor expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Efficacy for human ORL1 receptor expressing HEK293 cellsMore data for this Ligand-Target Pair
