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Report error Found 12 of affinity data for UniProtKB/TrEMBL: P38571
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318690(4-Piperidinyl-1,2,5-thiadiazolyl-3-morpholine carb...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318691(4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidin...)
Affinity DataIC50: 152nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318686(4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318687(4-(Azepan-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318689(4-Morpholino-1,2,5-thiadiazol-3-yl piperidine-1-ca...)
Affinity DataIC50: 424nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318692(4-(Pyrrolidin-1-yl)-1,2,5-thiadiazol-3-yl morpholi...)
Affinity DataIC50: 473nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318688(CHEMBL1082518 | cid_655946 | 3-N-Morpholinocarbama...)
Affinity DataIC50: 492nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50318693(4-(Pyrrolidin-1-yl)-1,2,5-thiadiazol-3-yl Piperidi...)
Affinity DataIC50: 496nMAssay Description:Inhibition of human LAL after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50287471(1-(4-tert-Butyl-cyclohexyl)-3,3,4,4,4-pentafluoro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pancreatic cholesterol esterase using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50287472(1-((S)-10,13-Dimethyl-17-octyl-hexadecahydro-cyclo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pancreatic cholesterol esterase using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50287473(3,3,4,4,4-Pentafluoro-1-((2S,4aS,8aS)-4a-methyl-de...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of pancreatic cholesterol esterase using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetLysosomal acid lipase/cholesteryl ester hydrolase(Human)
Weill Cornell Medical College

Curated by ChEMBL
LigandPNGBDBM50287474(3,3-Difluoro-1-((2S,4aS,8aS)-4a-methyl-decahydro-n...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of pancreatic cholesterol esterase using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article