Compile Data Set for Download or QSAR
Report error Found 89 of affinity data for UniProtKB/TrEMBL: P35991
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202131(US9233983, I-2)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202199(US9233983, P-14)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111998(US8618107, 312)
Affinity DataIC50: 6nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50569790(CHEMBL4852459)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50569791(CHEMBL4846828)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202122(US9233983, D-14)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202141(US9233983, I-12)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111952(US8618107, 210)
Affinity DataIC50: 10nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM467718((R)-N-(1-Acryloylpyrrolidin-3-yl)-5-(2-methyl-4-(2...)
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM467364((R)-N-(1-Acryloylpiperidin-3-yl)-5-(2-chloro-4-phe...)
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202130(US9233983, I-1)
Affinity DataIC50: 14nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202200(US9233983, P-15)
Affinity DataIC50: 15nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134365(CHEMBL3745935)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202196(US9233983, P-11)
Affinity DataIC50: 18nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM471715((R)-N-(1-Acryloylpiperidin-3-yl)-5-(2-fluoro-4-phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111951(US8618107, 197)
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50254270(CHEMBL4080943)
Affinity DataIC50: 25nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM467857(US10800792, Example 518 | (S)-N-(1-Acryloylpyrroli...)
Affinity DataIC50: 30nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202109(US9233983, D-1)
Affinity DataIC50: 32nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202105(US9233983, C-2)
Affinity DataIC50: 36nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134366(CHEMBL3746115)
Affinity DataIC50: 41nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202197(US9233983, P-12)
Affinity DataIC50: 42nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM467759(US10800792, Example 417 | US10800792, Example 418 ...)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202082(US9233983, B-1)
Affinity DataIC50: 48nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134323(CHEMBL3746036)
Affinity DataIC50: 50nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50450836(CHEMBL4216939)
Affinity DataIC50: 51nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50254273(CHEMBL4085292)
Affinity DataIC50: 51nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202127(US9233983, G-1)
Affinity DataIC50: 51nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134369(CHEMBL3747417)
Affinity DataIC50: 54nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202128(US9233983, G-2)
Affinity DataIC50: 54nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50254236(CHEMBL4090189)
Affinity DataIC50: 57nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202086(US9233983, B-5)
Affinity DataIC50: 59nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)
Affinity DataIC50: 60nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50064866(CHEMBL3401289)
Affinity DataIC50: 60nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111939(US8618107, 105)
Affinity DataIC50: 64nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202208(US9233983, P-23)
Affinity DataIC50: 75nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM485273(N-((1R,2S)-2-Acrylamidocyclopentyl)-5-(*S)-(2-meth...)
Affinity DataIC50: 80nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50064876(CHEMBL3401267)
Affinity DataIC50: 80nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202087(US9233983, B-6)
Affinity DataIC50: 81nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111938(US8618107, 104)
Affinity DataIC50: 87nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134368(CHEMBL3746333)
Affinity DataIC50: 90nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50: 91nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM111945(US8618107, 113)
Affinity DataIC50: 107nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50012060(CHEMBL3263640)
Affinity DataIC50: 112nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in mouse splenic B cells after 18 hrs by antibody-based FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM230107(US9334290, 32 | US10106559, Example 33 | US9850258...)
Affinity DataIC50: 130nMAssay Description:Inhibition of BTK in mouse whole blood assessed as reduction in anti-IgM/IgG-induced CD69 surface expression on peripheral B cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM467457(US10822348, Example 109 | N-(1-Acryloylazetidin-3-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of BTK in C57Bl/6 mouse splenocyte assessed as reduction in anti-IgM-induced CD69 expression incubated for 1 hr followed anti-IgM stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50254279(CHEMBL4060453)
Affinity DataIC50: 137nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50194720(CHEMBL3900554)
Affinity DataIC50: 140nMAssay Description:Inhibition of BTK in mouse whole blood assessed as suppression of BCR/anti-IgM/IgG-stimulated CD69 surface expression after 18 hrs with agitation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM36516(4-(tert-Butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morp...)
Affinity DataIC50: 150nMAssay Description:Inhibition of BTK-mediated CD86 surface expression in Balb/c mouse splenocytes preincubated for 60 mins before F(ab')2 anti-mouse IgM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase BTK(Mouse)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM202141(US9233983, I-12)
Affinity DataIC50: 159nMAssay Description:Inhibition of mouse BTK assessed as decrease in anti-mouse IgD antibody stimulated BCR mediated CD69 upregulation in whole blood preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
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