Compile Data Set for Download or QSAR
Report error Found 77 of affinity data for UniProtKB/TrEMBL: P35750
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114340(N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal | (S...)
Affinity DataIC50: 35nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114336((S)-2-(4-Fluoro-benzenesulfonylamino)-N-{(S)-1-[(2...)
Affinity DataIC50: 190nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114342((S)-N-{(S)-1-[(2-Dimethylamino-acetyl)-hydrazonome...)
Affinity DataIC50: 370nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114341((2S)-N-((1S)-1-{(E)-[(aminocarbonyl)hydrazono]meth...)
Affinity DataIC50: 680nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114337((S)-2-(4-Fluoro-benzenesulfonylamino)-3-methyl-N-{...)
Affinity DataIC50: 790nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114339((S)-2-(4-Fluoro-benzenesulfonylamino)-3-methyl-N-{...)
Affinity DataIC50: 6.20E+3nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50363928(CHEMBL1951575)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114338((S)-N-{2-[(2-Dimethylamino-acetyl)-hydrazono]-ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibitory activity against porcine erythrocyte Mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466172(CHEMBL366254 | PD-150606)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of porcine Calpain-1 active site domain using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466172(CHEMBL366254 | PD-150606)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466175(CHEMBL4289886)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466174(CHEMBL4293475)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466173(CHEMBL4288775)
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of porcine Calpain-1 active site domain using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50363928(CHEMBL1951575)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine Calpain-1 active site domain using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50466173(CHEMBL4288775)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length porcine Calpain-1 complex using (H2NeK(-FAM)-EVYGMMK(DABCYL)eOH) substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23865(3-[(2S)-2-[1-(9H-fluoren-9-yl)acetamido]-4-methylp...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543556(CHEMBL4647187)
Affinity DataKi:  9nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23866(benzyl N-[(1S)-2-methyl-1-[(1-oxo-3-phenylpropan-2...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014577(CHEMBL286722 | benzyl (S)-3-methyl-1-oxo-1-((S)-1-...)
Affinity DataKi:  10nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543555(CHEMBL4642092)
Affinity DataKi:  14nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543554(CHEMBL4646991)
Affinity DataKi:  16nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543552(CHEMBL4642290)
Affinity DataKi:  18nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193489((R)-1-(4-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  20nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326300(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  23nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193501((R)-1-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...)
Affinity DataKi:  33nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193494((R)-1-(4-methoxyphenylsulfonyl)-N-((R,S)-1-oxo-3-p...)
Affinity DataKi:  37nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23859(3-[(2S)-2-[1-(adamantan-1-yl)acetamido]-4-methylpe...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326298(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  41nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193509((S)-3-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...)
Affinity DataKi:  42nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23857(3-[(2S)-2-(3-cyclohexylpropanamido)-4-methylpentan...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326303(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  53nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326304(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...)
Affinity DataKi:  55nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23863(3-[(2S)-2-(3,3-diphenylpropanamido)-4-methylpentan...)
Affinity DataKi:  63nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193503((4S)-N-(1-oxo-3-phenylpropan-2-yl)-3-tosylthiazoli...)
Affinity DataKi:  70nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193502((S)-3-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  74nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50244952((S)-2-ethyl-N-(1-oxo-3-phenylpropan-2-yl)-2-(3-phe...)
Affinity DataKi:  80nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193507((2R)-N-(1-oxo-3-phenylpropan-2-yl)-1-tosylpyrrolid...)
Affinity DataKi:  81nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193490((S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  90nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM23861(3-[(2S)-2-(1,1-diphenylacetamido)-4-methylpentanam...)
Affinity DataKi:  108nM ΔG°:  -39.4kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2008
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193495((S)-3-(4-fluorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  110nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193504((R)-1-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  128nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193497((R)-1-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  141nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50084684({3-Methyl-1-[1-(3-morpholin-4-yl-propylaminooxalyl...)
Affinity DataKi:  150nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326299(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-amino-...)
Affinity DataKi:  165nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193506((R)-1-(naphthalen-1-ylsulfonyl)-N-((R,S)-1-oxo-3-p...)
Affinity DataKi:  191nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193493((R)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)-1-(phenyls...)
Affinity DataKi:  196nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50326306(3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(dimethyl...)
Affinity DataKi:  226nMAssay Description:Inhibition of porcine erythrocyte calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50193505((R)-1-(3-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  256nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Pig)
Senju Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50543553(CHEMBL4640485)
Affinity DataKi:  273nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
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