Compile Data Set for Download or QSAR
Report error Found 321 of affinity data for UniProtKB/TrEMBL: P35560
LigandPNGBDBM194954(US9206198, 7)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat Kir1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM350315(US10208064, Example 30)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM155924(US9018211, 5)
Affinity DataIC50: 7nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM155921(US9018211, 2A)
Affinity DataIC50: 9nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM350282(US10208064, Example 2)
Affinity DataIC50: 9nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM155923(US9018211, 2C)
Affinity DataIC50: 10nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM350300(US10208064, Example 19)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM155922(US9018211, 2B)
Affinity DataIC50: 12nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM162868(US9056859, 11)
Affinity DataIC50: 12nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM155925(US9018211, 12)
Affinity DataIC50: 13nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM155926(US9018211, 20)
Affinity DataIC50: 14nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat ROMK by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
LigandPNGBDBM155927(US9018211, 22 (isomer 2))
Affinity DataIC50: 15nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM50505263(CHEMBL4586813)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM408663(US10364234, Example 1 | US10759788, Example 1 | (R...)
Affinity DataIC50: 18.7nMAssay Description:human ROMK and rat ROMK: 1. Materials and Instruments (1) FluxOR potassium ion channel assay (F10016, Invitrogen) (2) Ouabain (03125-1G, Sigma)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
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LigandPNGBDBM162872(US9056859, 72)
Affinity DataIC50: 20nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM155929(US9018211, 55)
Affinity DataIC50: 23nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM162870(US9056859, 48)
Affinity DataIC50: 35nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM155928(US9018211, 52)
Affinity DataIC50: 36nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
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LigandPNGBDBM162874(US9056859, 122)
Affinity DataIC50: 37nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM50249183(CHEMBL4069245)
Affinity DataIC50: 38nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed
LigandPNGBDBM163767(US9062070, 22)
Affinity DataIC50: 40nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM50235196(CHEMBL4064760)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50235198(CHEMBL4066256)
Affinity DataIC50: 40nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50505261(CHEMBL4456474)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM163826(US9062070, 81 | US9062070, 82)
Affinity DataIC50: 50nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50: 55nMAssay Description:Inhibition of rat ROMK channel expressed in HEk293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM162876(US9056859, 217)
Affinity DataIC50: 56nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM162872(US9056859, 72)
Affinity DataIC50: 56nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
LigandPNGBDBM163759(US9062070, 15)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163770(US9062070, 25)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163800(US9062070, 55 | US9062070, 56)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163826(US9062070, 81 | US9062070, 82)
Affinity DataIC50: 60nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM162872(US9056859, 72)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat ROMK assessed as thallium flux after 30 mins in presence of ouabain by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50235197(CHEMBL4086237)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50235200(CHEMBL4098260)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2019
Entry Details Article
PubMed
LigandPNGBDBM50442595(CHEMBL2441408 | US9056859, 12)
Affinity DataIC50: 61nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM162873(US9056859, 96)
Affinity DataIC50: 61nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM162869(US9056859, 39)
Affinity DataIC50: 63nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM50442600(CHEMBL2441437 | US9056859, 1)
Affinity DataIC50: 65nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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LigandPNGBDBM163777(US9062070, 32)
Affinity DataIC50: 70nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM50163355(CHEMBL3793685)
Affinity DataIC50: 70nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50163368(CHEMBL3794427)
Affinity DataIC50: 73nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50163353(CHEMBL3793380)
Affinity DataIC50: 79nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
LigandPNGBDBM163750(US9062070, 6 | US9062070, 7)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163765(US9062070, 20)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163766(US9062070, 21)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163776(US9062070, 31)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163794(US9062070, 49)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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LigandPNGBDBM163828(US9062070, 83)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
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