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Report error Found 493 for UniProtKB: P35355
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472616(CHEMBL65325)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472618(CHEMBL303092)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472623(CHEMBL294100)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472624(CHEMBL62439)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472627(CHEMBL304489)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472632(CHEMBL65140)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472613(CHEMBL305076)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472605(CHEMBL64507)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472612(CHEMBL60496)
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289082(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289084(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289083(3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289088(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289081(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472615(CHEMBL64813)
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM22970(2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472610(CHEMBL60725)
Affinity DataIC50: 9.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472622(CHEMBL291543)
Affinity DataIC50: 9.5nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076666(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076661(N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472631(CHEMBL60738)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50075539(CHEMBL1626563 | CHEMBL17229 | 3-(3,5-Di-tert-butyl...)
Affinity DataIC50: 11nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472619(CHEMBL62990)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472625(CHEMBL62920)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289090({1-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289089(2-[1-(4-Chloro-benzyl)-5-methoxy-2-methyl-1H-indol...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289091((S)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-in...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50012860(CHEMBL61422 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472603(CHEMBL65330)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076637(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076659(N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50223539(CHEMBL33957)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472609(CHEMBL64585)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076650(N-Hydroxy-N-{3-[1-(4-methoxy-phenyl)-5-p-tolyl-1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50279050(CHEMBL4169347)
Affinity DataIC50: 48nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50260464(CHEMBL4071383)
Affinity DataIC50: 49nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289087(4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50003117(CHEMBL331489 | 3-(3,5-Di-tert-butyl-4-hydroxy-phen...)
Affinity DataIC50: 50nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50076642(2,2,2-Trifluoro-N-hydroxy-N-{3-[1-(4-methoxy-pheny...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50223541(Clofurac)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50260465(CHEMBL4101003)
Affinity DataIC50: 53nMAssay Description:Inhibition of COX-2 in rat peritoneal macrophages assessed as reduction in PGE2 production using radiolabelled-arachidonic acid as substrate pretreat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50472604(CHEBI:35847 | CP-66,248 | Tenidap)
Affinity DataIC50: 53nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50279037(CHEMBL4173526)
Affinity DataIC50: 56nMAssay Description:Inhibition of rat kidney microsomal COX assessed as PGE2 level using arachidonic acid as substrate preincubated for 5 to 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289086((2R,3S)-3-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289092(L-761066 | (R)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-m...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

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