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Report error Found 37 for UniProtKB: P33260
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105809(4-Amino-N-isopropyl-N-(2-phenyl-2H-pyrazol-3-yl)-b...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105810(3'-Amino-biphenyl-4-sulfonic acid (3-hydroxy-propy...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105811(3'-Nitro-biphenyl-4-sulfonic acid (4-hydroxy-butyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105812(3'-Nitro-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461264(US10774056, Compound 028 | US11542242, Compound 02...)
Affinity DataIC50: 5.90E+3nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105825(4-Amino-N-butyl-N-(2-phenyl-2H-pyrazol-3-yl)-benze...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105821(4-Amino-N-ethyl-N-(2-phenyl-2H-pyrazol-3-yl)-benze...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105820(4-Amino-N-benzyl-N-(2-phenyl-2H-pyrazol-3-yl)-benz...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105808(3'-Nitro-biphenyl-4-sulfonic acid (3-hydroxy-propy...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105816(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-N-propyl-benz...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105817(3'-Nitro-biphenyl-4-sulfonic acid (2-hydroxy-ethyl...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105814(4-Amino-N-(3-methyl-butyl)-N-(2-phenyl-2H-pyrazol-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461268(US10774056, Compound 032 | US11542242, Compound 03...)
Affinity DataIC50: 9.50E+3nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50508661(CHEMBL4524830)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP450More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461261(US10774056, Compound 025 | US11542242, Compound 02...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461260(US10774056, Compound 022 | US11542242, Compound 02...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461258(US10774056, Compound 007 | US11542242, Compound 00...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461256(US10774056, Compound 003 | US11542242, Compound 00...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461257(US10774056, Compound 006 | US11542242, Compound 00...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461263(US10774056, Compound 027 | US11542242, Compound 02...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105828(4-Allyl-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461266(US10774056, Compound 030 | US11542242, Compound 03...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 1A2/2C18/2C19(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM461267(US10774056, Compound 031 | US11542242, Compound 03...)
Affinity DataIC50: 1.00E+4nMAssay Description:For Cyp inhibition, human liver microsomes from BD Gentest were incubated with Compound 028 or Compound 032 (10, 3.33, 1.11, 0.37, 0.12, 0.04, 0.01 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent

TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105824(4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZ...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105818(4-Amino-N-methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benz...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105815(4-Allyl-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50548260(Pongapin)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C18 expressed in Sacchrosomes by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50548258(LANCEOLATIN B)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C18 expressed in Sacchrosomes by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105822(3'-Amino-biphenyl-4-sulfonic acid (2-phenyl-2H-pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105823(4-Methyl-N-(2-phenyl-2H-pyrazol-3-yl)-N-propyl-ben...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105826(4-(3-Amino-propyl)-N-(3-hydroxy-propyl)-N-(2-pheny...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105819(4-Amino-N-(3-hydroxy-propyl)-N-(2-phenyl-2H-pyrazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090677(CHEMBL1109 | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105807(4-(2-Amino-ethyl)-N-(3-hydroxy-propyl)-N-(2-phenyl...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105813(4-Allyl-N-benzyl-N-(2-phenyl-2H-pyrazol-3-yl)-benz...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50105827(4-Allyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C18(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50090669(4-Methyl-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfo...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibitory effect on human recombinant liver cytochrome P450 2C18 expressed in yeast strainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed