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TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM159790(US9040501, 876400)
Affinity DataIC50: 101nMpH: 7.4Assay Description:The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
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TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50421666(CHEMBL2311128 | US9040501, 876404)
Affinity DataIC50: 113nMpH: 7.4Assay Description:The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM159792(US9040501, 878895)
Affinity DataIC50: 140nMpH: 7.4Assay Description:The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007030(CHEMBL3237548)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111578(US8618075, 2a)
Affinity DataIC50: 200nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
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TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM159789(US9040501, 876437)
Affinity DataIC50: 237nMpH: 7.4Assay Description:The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007025(TETRAHYDROURIDINE)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111577(US8618075, 1a)
Affinity DataIC50: 400nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007031(CHEMBL3237549)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007029(CHEMBL3237547)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111585(US8618075, 3a)
Affinity DataIC50: 400nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111579(US8618075, 1)
Affinity DataIC50: 400nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM159791(US9040501, 878519)
Affinity DataIC50: 1.62E+3nMpH: 7.4Assay Description:The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111582(US8618075, 3)
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111581(US8618075, 2)
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111580(US8618075, 3b)
Affinity DataIC50: 4.00E+3nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007033(CHEMBL3237551)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111584(US8618075, 2b)
Affinity DataIC50: 5.00E+3nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM111583(US8618075, 1b)
Affinity DataIC50: 5.00E+3nMpH: 7.4Assay Description:The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007032(CHEMBL3237550)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007034(CHEMBL3237552)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007028(CHEMBL3237546)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007026(CHEMBL3237544)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007027(CHEMBL3237545)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007036(CHEMBL3237554)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007035(CHEMBL3237553)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50065262(1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydr...)
Affinity DataKi:  0.00120nMAssay Description:Compound was tested for its binding affinity against cytidine deaminase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50367034(CHEMBL610997)
Affinity DataKi:  25nMAssay Description:Binding affinity for human cytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50367034(CHEMBL610997)
Affinity DataKi:  25nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50391219(CHEMBL2093931)
Affinity DataKi:  40nMAssay Description:Cytidine Deaminase Inhibition in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50391219(CHEMBL2093931)
Affinity DataKi:  40nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50421666(CHEMBL2311128 | US9040501, 876404)
Affinity DataKi:  100nMAssay Description:Cytidine Deaminase Inhibition in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50366986(CHEMBL607779)
Affinity DataKi:  400nMAssay Description:Cytidine Deaminase Inhibition in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50025464(1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  400nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50366986(CHEMBL607779)
Affinity DataKi:  400nMAssay Description:Binding affinity for human cytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50421666(CHEMBL2311128 | US9040501, 876404)
Affinity DataKi:  400nMAssay Description:Binding affinity for human cytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50391219(CHEMBL2093931)
Affinity DataKi:  900nMAssay Description:Cytidine Deaminase Inhibition in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50367350(CHEMBL603590)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity for human cytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50065260(1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydr...)
Affinity DataKi:  2.30E+3nMAssay Description:Apparent Ki (binding affinity) was calculated for the compound against cytidine deaminase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50366985(CHEMBL608656)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50366987(CHEMBL608479)
Affinity DataKi:  9.00E+3nMAssay Description:Cytidine Deaminase Inhibition in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50367036(CHEMBL609349)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50065260(1-((3R,4S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydr...)
Affinity DataKi:  3.80E+4nMAssay Description:Compound was tested for its binding affinity against cytidine deaminase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007037(CHEMBL3237555 | CHEBI:23774)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human cytidine deaminase by spectrophotometricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50065261(1-((4R,5S)-4,5-Dihydroxy-3-hydroxymethyl-cyclopent...)
Affinity DataKi:  1.00E+5nMAssay Description:Compound was tested for its binding affinity against cytidine deaminase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50087289(4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-o...)
Affinity DataKi:  1.90E+5nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50367035(CHEMBL608655)
Affinity DataKi:  3.00E+5nMAssay Description:Binding affinity against cytidine deaminase of human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007025(TETRAHYDROURIDINE)
Affinity DataKi:  4.40E+5nMAssay Description:Inhibition of human cytidine deaminase by spectrophotometricallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50421893(CHEMBL10128)
Affinity DataKi:  7.69E+6nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCytidine deaminase(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM50007156(4-Amino-5-fluoro-1-(4-hydroxy-5-hydroxymethyl-3-me...)
Affinity DataKi:  2.51E+7nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
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