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Report error Found 1368 for UniProtKB: P32305
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataIC50: 220nMAssay Description:Evaluated for inhibition of specific [3H]5-HT receptor binding in rat cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060429((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...)
Affinity DataIC50: 540nMAssay Description:Compound was tested for the displacement of [3H]5-HT binding to cloned rat 5-hydroxytryptamine 7 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50028124(CHEMBL337825 | 6-MeOT | 2-(6-methoxy-1H-indol-3-yl...)
Affinity DataIC50: 630nMAssay Description:Evaluated for inhibition of specific [3H]5-HT receptor binding in rat cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity at serotonin 5-HT1-type site receptor in rat cortex by displacing [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: 1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM234388(3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b...)
Affinity DataIC50: 1.00E+4nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.0290nMAssay Description:Binding affinity against Rat 5-hydroxytryptamine 7 receptor using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM29568([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21383(6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...)
Affinity DataKi:  0.130nM ΔG°:  -58.7kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nM ΔG°:  -57.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat cloned 5-Hydroxytryptamine receptor 7 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21367(CHEMBL225284 | 6-{4-[2-(methylsulfanyl)phenyl]pipe...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]LSD from rat recombinant 5-HT7 receptor expressed in HEK293 cell membranes incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474418(CHEMBL611472)
Affinity DataKi:  0.251nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22872(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.450nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22867(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.510nMAssay Description:Binding affinity to the rat 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21392([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22867(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
Affinity DataKi:  0.520nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM22867(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
Affinity DataKi:  0.520nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  0.570nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  0.570nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat cloned 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50253281(N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  0.603nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50213542(di-2-[[3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-et...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  0.630nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007692(TIOSPERONE | CHEMBL35057 | CHEMBL1204189 | 8-[4-(4...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM81444(NSC_185453 | CAS_185453 | WB 4101 | WB-4101)
Affinity DataKi:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details Article
PubMed
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