Compile Data Set for Download or QSAR
Report error Found 5409 of affinity data for UniProtKB/TrEMBL: P31652
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010589(CHEMBL162375 | 6,7-Dihydro-5H-indeno[5,6-d][1,3]di...)
Affinity DataKd:  0.127nMAssay Description:Binding affinity was determined towards serotonin uptake site in presence of [3H]paroxetine radioligand in rat hippocampal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKd:  0.0510nMAssay Description:Binding affinity of the radio labeled [3H]5-Methyl-6-nitroquipazine compound against Serotonin transporter in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50121451(5-Methyl-6-nitro-2-piperazin-1-yl-quinoline | CHEM...)
Affinity DataKd:  0.0510nMAssay Description:Binding affinity of the radio labeled [3H]5-Methyl-6-nitroquipazine compound against Serotonin transporter in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKd:  0.150nMAssay Description:The potency of the [3H]paroxetine for 5-HT transportersMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010589(CHEMBL162375 | 6,7-Dihydro-5H-indeno[5,6-d][1,3]di...)
Affinity DataKd:  0.104nMAssay Description:Binding affinity was determined towards serotonin uptake site in presence of [3H]paroxetine radioligand in rat brain cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023178(CHEMBL3298873)
Affinity DataEC50:  410nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50014210(3-(2-Aminopropyl)indole | CHEMBL30713 | DL-3-(2-Am...)
Affinity DataEC50:  22nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023177(CHEMBL3298871)
Affinity DataEC50:  181nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50114074(CHEMBL3603955)
Affinity DataEC50:  91nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025221(CHEMBL1906905)
Affinity DataEC50:  16nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025212(CHEMBL3330646)
Affinity DataEC50:  68nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023162(CHEMBL3298862)
Affinity DataEC50:  562nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50114075(CHEMBL3603956)
Affinity DataEC50:  573nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataEC50:  74nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM84738(NSC_3337 | CAS_16105-77-4 | Fenfluramine (-) | d-F...)
Affinity DataEC50:  108nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50302907(2-(N-Cyclopropylamino)-3-chloropropiophenone | CHE...)
Affinity DataEC50:  1.33E+3nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025198(Etryptamine)
Affinity DataEC50:  23nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM86239(NSC_3046161 | CAS_3046161 | MDA,R(-))
Affinity DataEC50:  310nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025197(CHEMBL96816)
Affinity DataEC50:  14nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023176(CHEMBL3298869)
Affinity DataEC50:  667nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50028124(CHEMBL337825 | 6-MeOT | 2-(6-methoxy-1H-indol-3-yl...)
Affinity DataEC50:  54nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005247(CHEMBL6731 | MDA | (S)-(+)-2-Benzo[1,3]dioxol-5-yl...)
Affinity DataEC50:  160nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50114072(CHEMBL3603954)
Affinity DataEC50:  117nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023163(CHEMBL3298863)
Affinity DataEC50:  733nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50073691(5-Methyl-tryptamine, 10 | CHEMBL331241 | 5-Methylt...)
Affinity DataEC50:  139nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50331288(CHEMBL1288717 | 5-Br-T | 2-(5-bromo-1H-indol-3-yl)...)
Affinity DataEC50:  75nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025215(CHEMBL3330641)
Affinity DataEC50:  53nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023161(CHEMBL3298870)
Affinity DataEC50:  356nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025220(CHEMBL3330644)
Affinity DataEC50:  45nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023165(CHEMBL3298865)
Affinity DataEC50:  621nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50236728(CHEMBL4086874)
Affinity DataEC50:  134nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025214(CHEMBL3330640)
Affinity DataEC50:  19nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50024210(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
Affinity DataEC50:  33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50331286(CHEMBL1288716 | 5-Cl-T | 2-(5-chloro-1H-indol-3-yl...)
Affinity DataEC50:  19nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023173(CHEMBL3298866)
Affinity DataEC50:  1.07E+3nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025222(CHEMBL3330647)
Affinity DataEC50:  33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50236724(CHEMBL4084187)
Affinity DataEC50:  1.77E+3nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50029103(2-(3-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL14...)
Affinity DataEC50:  120nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023179(CHEMBL3298874)
Affinity DataEC50:  4.70E+3nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025219(CHEMBL3330643)
Affinity DataEC50:  8nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025213(CHEMBL3330648)
Affinity DataEC50:  37nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataEC50:  61nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025218(CHEMBL204839)
Affinity DataEC50:  24nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025216(CHEMBL382635)
Affinity DataEC50:  108nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50114071(CHEMBL3604009)
Affinity DataEC50:  347nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50025200(CHEMBL3330645)
Affinity DataEC50:  20nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50241050(6-fluorotryptamine | 2-(6-fluoro-1H-indol-3-yl)eth...)
Affinity DataEC50:  4.40nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50276189(1-(2-Naphthyl)-2-aminopropane | CHEMBL471839)
Affinity DataEC50:  3.40nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM30853(MLS000047815 | 5-F-T | CHEMBL275628 | cid_197774 |...)
Affinity DataEC50:  10nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50023175(CHEMBL3298868)
Affinity DataEC50:  1.63E+3nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
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