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TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  377nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55081(ML182 | VU0400195-3 | cid_46869947)
Affinity DataEC50:  594nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50034501((S)-Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic...)
Affinity DataEC50:  8.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM17660(2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)prop...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50034501((S)-Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic...)
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202131(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50156082(N-(4-bromo-2-((1,3-dioxoisoindolin-2-yl)methyl)phe...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50156070(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202127(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202120(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202130(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202124(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202142(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202135(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202121(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202118(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202128(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202134(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50202143(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50342742(4-(3,5-Difluorophenyl)-N-(1-[2-chlorophenyl]-3-phe...)
Affinity DataEC50:  646nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50342741(3-Cyano-4-(1-naphthyl)-N-(1-[2-chlorophenyl]-3-phe...)
Affinity DataEC50:  2.17E+3nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50342738(3-Cyano-4-phenyl-N-(1-[2-chlorophenyl]-3-phenyl-1H...)
Affinity DataEC50:  4.14E+3nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50342740(3-Cyano-4-(4-fluorophenyl)-N-(1-[2-chlorophenyl]-3...)
Affinity DataEC50:  2.43E+3nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50342739(3-Cyano-4-(3-fluorophenyl)-N-(1-[2-chlorophenyl]-3...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022760(CHEMBL3298458)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022762(CHEMBL3298459)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022763(CHEMBL3298462)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022765(CHEMBL3298465)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022767(CHEMBL3297929)
Affinity DataEC50:  7.76E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022768(CHEMBL3298284)
Affinity DataEC50:  3.16E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022769(CHEMBL3298456)
Affinity DataEC50:  2.75E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022770(CHEMBL3298283)
Affinity DataEC50:  2.46E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022778(CHEMBL3297927)
Affinity DataEC50:  1.62E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022779(CHEMBL3298272)
Affinity DataEC50:  1.18E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022780(CHEMBL3298461)
Affinity DataEC50:  1.15E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022783(CHEMBL3298271)
Affinity DataEC50:  1.05E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022797(CHEMBL3298464)
Affinity DataEC50:  589nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022798(CHEMBL3297918)
Affinity DataEC50:  537nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022813(CHEMBL3298282)
Affinity DataEC50:  447nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022814(CHEMBL3297922)
Affinity DataEC50:  407nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022759(CHEMBL3298273)
Affinity DataEC50:  224nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022816(CHEMBL3298453)
Affinity DataEC50:  214nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022818(CHEMBL3297750)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022819(CHEMBL3298452)
Affinity DataEC50:  117nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022820(CHEMBL3298463)
Affinity DataEC50:  98nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022821(CHEMBL3298275)
Affinity DataEC50:  62nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022796(CHEMBL3297923)
Affinity DataEC50:  640nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50022782(CHEMBL3297924)
Affinity DataEC50:  1.09E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
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