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Report error Found 270 for UniProtKB: P31388
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataIC50: 220nMAssay Description:Evaluated for inhibition of specific [3H]5-HT receptor binding in rat cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50028124(CHEMBL337825 | 6-MeOT | 2-(6-methoxy-1H-indol-3-yl...)
Affinity DataIC50: 630nMAssay Description:Evaluated for inhibition of specific [3H]5-HT receptor binding in rat cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]5-HT binding to rat 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity at serotonin 5-HT1-type site receptor in rat cortex by displacing [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50151982(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of rat hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50060429((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for the displacement of [3H]5-HT binding to cloned rat 5-hydroxytryptamine 6 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50318633(SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...)
Affinity DataKi:  0.234nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50318633(SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...)
Affinity DataKi:  0.234nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22872(1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl...)
Affinity DataKi:  0.410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM28583(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50130286(SB-258510 | CHEMBL29846 | 5-Chloro-3-methyl-benzo[...)
Affinity DataKi:  0.760nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50019754(LU-AE58054 | IDALOPIRDINE)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50019754(LU-AE58054 | IDALOPIRDINE)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  1.05nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM35255(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Affinity DataKi:  1.17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50130268(N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(pipera...)
Affinity DataKi:  1.41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  1.51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  1.81nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  1.84nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  1.86nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM86428(SB-258585)
Affinity DataKi:  2.29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50027065(12'-hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergota...)
Affinity DataKi:  2.34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM82479(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM86427(NSC_3981 | CAS_50-37-3 | LSD)
Affinity DataKi:  2.63nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50130257(CHEMBL90125 | (E)-chlorprothixene | CHLORPROTHIXEN...)
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50024202(5-OH-ME-Nw Tryptamine | CHEMBL277362 | 5-HT,omega-...)
Affinity DataKi:  3.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50130257(CHEMBL90125 | (E)-chlorprothixene | CHLORPROTHIXEN...)
Affinity DataKi:  3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  3.71nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM78940(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-LSD from rat 5-Ht6 receptor expressed in HEK cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataKi:  3.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22869(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50024206(3-[2-(dimethylamino)ethyl]indol-5-ol | 5-hydroxy-N...)
Affinity DataKi:  4.46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50073056(CHEMBL292759 | SB-214111 | 4-Bromo-N-[4-methoxy-3-...)
Affinity DataKi:  4.79nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22867(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
Affinity DataKi:  5.24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22867(3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50280055(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
Affinity DataKi:  5.37nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50280055(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
Affinity DataKi:  5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50001786(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
Affinity DataKi:  5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22870(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22870(CHEMBL1113 | Asendin | 2-chloro-11-piperazin-1-yld...)
Affinity DataKi:  6.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2012
Entry Details Article
PubMed
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