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Report error Found 3 of affinity data for UniProtKB/TrEMBL: P30876
TargetDNA-directed RNA polymerase II subunit RPB2(Homo sapiens)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  104nMAssay Description:Binding affinity against POLR2B (unknown origin) assessed as apparent dissociation constant incubated for 1 hr by colloidal coomassie staining based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-directed RNA polymerase II subunit RPB2(Homo sapiens)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 150nMAssay Description:Inhibition of POLR2B (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA-directed RNA polymerase II subunit RPB2(Homo sapiens)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  181nMAssay Description:Binding affinity to human POLR2B incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed