Compile Data Set for Download or QSAR
Report error Found 375 of affinity data for UniProtKB/TrEMBL: P30536
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  6nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50255226(SR-180575 | (7-chloro-N,N,5-trimethyl-4-oxo-3-phen...)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50045877(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Affinity DataKd:  4nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50336914(3-[(21S,22S)-16-ethenyl-11-ethyl-12,17,21,26-tetra...)
Affinity DataKd:  40nMAssay Description:Binding affinity to PBRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  11nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50210940(CHEMBL3948914)
Affinity DataKd:  108nMAssay Description:Binding affinity to recombinant human TSPO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50279019(CHEMBL1315992)
Affinity DataKd:  40nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  11nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50279015(CHEMBL4174207)
Affinity DataKd:  61nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588818(CHEMBL5174807)
Affinity DataEC50:  3.90E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50274258(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Affinity DataEC50:  571nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588816(CHEMBL5191240)
Affinity DataEC50:  6.99E+3nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50060095(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataEC50:  337nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588817(CHEMBL5193551)
Affinity DataEC50:  1.59E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588819(CHEMBL5194870)
Affinity DataEC50:  2.12E+4nMAssay Description:Inhibition of TSPO (unknown origin) in mouse MA-10 cells assessed as increase in steroid steroidogenesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378901(CHEMBL1672418)
Affinity DataKd:  10nMAssay Description:Binding affinity to human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50054139((R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic a...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human TSPOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50122293(CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50185957(N-(4-chloro-2-phenoxyphenyl)-N-(2-isopropoxybenzyl...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50210943(CHEMBL3970955)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50530439(CHEMBL4456416)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50530439(CHEMBL4456416)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588812(CHEMBL5179737)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of TSPO receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50229594(N-(2-methoxybenzyl)-N-(4-phenoxypyridin-3-yl)aceta...)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]-PK11195 from TSPO receptor in human Leucocyte incubated for 30 mins by beta-counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50588813(CHEMBL5199978)
Affinity DataIC50: 8.30nMAssay Description:Displacement of [3H]-PK11195 from TSPO receptor in human Leucocyte incubated for 30 mins by beta-counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50060121(2-(6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50060121(2-(6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378900(CHEMBL1672415)
Affinity DataIC50: 210nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50336914(3-[(21S,22S)-16-ethenyl-11-ethyl-12,17,21,26-tetra...)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50012189(CHEMBL3265238)
Affinity DataIC50: 350nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataIC50: 490nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378901(CHEMBL1672418)
Affinity DataIC50: 620nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50012191(CHEMBL3265237)
Affinity DataIC50: 680nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM220447(US9296741, 36 | US10633379, Compound X)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at peripheral benzodiazepine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378902(CHEMBL1672414)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50105061(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 1.04E+3nMAssay Description:Binding affinity for peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50012190(CHEMBL2442625)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of TSPO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50231767(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378903(CHEMBL1672412)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378904(CHEMBL1672411)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50378905(CHEMBL1672410)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50422188(Ro-06-9098 | MOTRAZEPAM)
Affinity DataIC50: 2.32E+6nMAssay Description:Binding affinity of compound towards Benzodiazepine receptor in a competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50422186(Ro-05-3072 | CHEMBL147144)
Affinity DataIC50: 2.58E+6nMAssay Description:Binding affinity of compound towards Benzodiazepine receptor in a competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
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