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TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235343(CHEMBL4103249)
Affinity DataIC50: 1nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235335(CHEMBL4092981)
Affinity DataIC50: 2nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235348(CHEMBL4078988)
Affinity DataIC50: 3nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235346(CHEMBL4102518)
Affinity DataIC50: 8nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235347(CHEMBL4078246)
Affinity DataIC50: 10nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235349(CHEMBL4065402)
Affinity DataIC50: 17nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235336(CHEMBL4085238)
Affinity DataIC50: 18nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235344(CHEMBL4086832)
Affinity DataIC50: 19nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235354(CHEMBL4069161)
Affinity DataIC50: 19nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235345(CHEMBL4105278)
Affinity DataIC50: 24nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235340(CHEMBL4101626)
Affinity DataIC50: 26nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235337(CHEMBL4062554)
Affinity DataIC50: 26nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235355(CHEMBL4081027)
Affinity DataIC50: 39nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235334(CHEMBL4070391)
Affinity DataIC50: 44nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235356(CHEMBL4097571)
Affinity DataIC50: 52nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572073((R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)a...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572074((R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)a...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572075(US11447493, Example 58 | (R)-2-((1-(4- acrylamidob...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572078((R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572091((R)-2-((1-(4- propionamidobenzoyl)pyrrolidin-3- yl...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572092((R)-2-((1-(4- propionamidobenzoyl)pyrrolidin-3- yl...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572075(US11447493, Example 58 | (R)-2-((1-(4- acrylamidob...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572094((R)-N,N-dimethyl-2-((1-(4- propionamidobenzoyl)pyr...)
Affinity DataIC50: 100nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235353(CHEMBL4090226)
Affinity DataIC50: 220nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2(Bovine)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50235332(CHEMBL4094205)
Affinity DataIC50: 290nMAssay Description:Inhibition of human GST-tagged CDK2/bovine His-tagged Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572060((R)-N-(4-(3-((6-chloroquinazolin-2- yl)amino)pyrro...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572061((R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- ...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572062((R)-N-(4-(3-(isoquinolin-3- ylamino)pyrrolidine-1-...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572063((R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)pyrro...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572066((R)-N-(4-(3-(pyrido[3,4-d]pyrimidin- 2-ylamino)pyr...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572067((R)-N-(4-(3-((7-methylquinazolin-2- yl)amino)pyrro...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572068((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572068((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572069((R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrr...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572071((R)-N-(4-(3-((7-chloroquinazolin-2- yl)amino)pyrro...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572072((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572072((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572076((R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)a...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572077((R)-N-(4-(3-((7-oxo-7,8- dihydropyrido[2,3-d]pyrim...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572078((R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572086((R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrr...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572087((R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572088((R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrr...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572090((R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrol...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572096((R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572096((R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the protein kinase. All kinase assays w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572097((R)-N-(2-fluoro-4-(3-(quinazolin-2- ylamino)pyrrol...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572100((R,E)-4-(dimethylamino)-N-(4-(3- (quinazolin-2-yla...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572102((R)-N-(5-(3-(quinazolin-2- ylamino)pyrrolidine-1- ...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM572105((R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- ...)
Affinity DataIC50: 550nMAssay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of the three protein kinases. All kinase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

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