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Report error Found 163 of affinity data for UniProtKB/TrEMBL: P28776
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM29612(N-Acetyltryptamine,5-Hydroxy | CHEMBL33103 | Norme...)
Affinity DataEC50:  2.10E+4nMAssay Description:Positive allosteric modulation of recombinant mouse IDOL transfected in mouse P1.HTR cells assessed as increase in Kyn production incubated for 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50633100(CHEMBL5412818)
Affinity DataEC50:  2.32E+6nMAssay Description:Inhibition of IDO1 in mouse CT26 cells using L-Tryptophan as substrate incubated for 24 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataEC50:  2.82E+6nMAssay Description:Inhibition of IDO1 in mouse CT26 cells using L-Tryptophan as substrate incubated for 24 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578623(CHEMBL4858888)
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578625(CHEMBL4855340)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50391363(CHEMBL2148074)
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550026(CHEMBL4786690)
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550026(CHEMBL4786690)
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578624(CHEMBL4856710)
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550030(CHEMBL4743409)
Affinity DataIC50: 3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559669(CHEMBL4756822)
Affinity DataIC50: 3nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559672(CHEMBL4750211)
Affinity DataIC50: 3nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571884(CHEMBL4859400)
Affinity DataIC50: 3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571886(CHEMBL4861763)
Affinity DataIC50: 3nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50285416(CHEMBL4161733)
Affinity DataIC50: 5nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559671(CHEMBL4750659)
Affinity DataIC50: 5nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50285416(CHEMBL4161733)
Affinity DataIC50: 5nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578625(CHEMBL4855340)
Affinity DataIC50: 5.80nMAssay Description:In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice da...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559678(CHEMBL4763467)
Affinity DataIC50: 6nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571881(CHEMBL4845988)
Affinity DataIC50: 6nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571885(CHEMBL4877466)
Affinity DataIC50: 6nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571883(CHEMBL4868709)
Affinity DataIC50: 7nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50549535(CHEMBL4763375)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of mouse IDO1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50514760(CHEMBL4448402)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571880(CHEMBL4851220)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550037(CHEMBL4755937)
Affinity DataIC50: 12nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550037(CHEMBL4755937)
Affinity DataIC50: 12nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50514753(CHEMBL4557994)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559681(CHEMBL4750132)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571879(CHEMBL4848094)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578622(CHEMBL4861332)
Affinity DataIC50: 14nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571887(CHEMBL4859579)
Affinity DataIC50: 16nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50391358(CHEMBL2147989)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50550028(CHEMBL4747228)
Affinity DataIC50: 20nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50391359(CHEMBL2147998)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559680(CHEMBL4780978)
Affinity DataIC50: 22nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571882(CHEMBL4860353)
Affinity DataIC50: 22nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM17467(5-(3-bromophenyl)-1H-1,2,3-triazole | 1,2,3-triazo...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578621(CHEMBL4853212)
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578626(CHEMBL4870435)
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578649(CHEMBL4866113)
Affinity DataIC50: 23nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse Panc02 cells incubated for 48 hrs by RFMS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50578624(CHEMBL4856710)
Affinity DataIC50: 25nMAssay Description:In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered as singl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50529361(CHEMBL4515137 | US10988487, Example 52)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse IDO1 preincubated for 30 mins followed by substrate tryptophan addition and measured after 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50391365(CHEMBL2147990)
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50391372(CHEMBL2147992)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559679(CHEMBL4752094)
Affinity DataIC50: 31nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50571891(CHEMBL4849714)
Affinity DataIC50: 31nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559673(CHEMBL4779097)
Affinity DataIC50: 36nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Nebraska

Curated by ChEMBL
LigandPNGBDBM50559677(CHEMBL4746203)
Affinity DataIC50: 36nMAssay Description:Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
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