Compile Data Set for Download or QSAR
Report error Found 155 of affinity data for UniProtKB/TrEMBL: P28572
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50361576(CHEMBL1939498 | CHEMBL1939497)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to GlyT1 in rat cortical brain homogenate after 60 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457704(CHEMBL4202565)
Affinity DataIC50: 2nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457706(CHEMBL4216391)
Affinity DataIC50: 3nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457693(CHEMBL4218366)
Affinity DataIC50: 3nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195169(2,4-dichloro-N-((4-(morpholine-4-carbonyl)-1-(prop...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457685(CHEMBL4210484)
Affinity DataIC50: 4nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457694(CHEMBL4211535)
Affinity DataIC50: 4nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457689(CHEMBL4206403)
Affinity DataIC50: 4nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457692(CHEMBL4211012)
Affinity DataIC50: 4nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457695(CHEMBL4217712)
Affinity DataIC50: 4nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543922(CHEMBL4640428)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543917(CHEMBL4638182)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195181(2,4-dichloro-5-fluoro-N-((4-(morpholine-4-carbonyl...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457714(CHEMBL4214756)
Affinity DataIC50: 8nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457691(CHEMBL4209849)
Affinity DataIC50: 9nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457688(CHEMBL4206639)
Affinity DataIC50: 9nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195173(2-chloro-4-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457703(CHEMBL4214250)
Affinity DataIC50: 10nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457710(CHEMBL4210353)
Affinity DataIC50: 10nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543918(CHEMBL4646639)
Affinity DataIC50: 10nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457687(CHEMBL4205471)
Affinity DataIC50: 12nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457702(CHEMBL4205995)
Affinity DataIC50: 12nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457712(CHEMBL4206122)
Affinity DataIC50: 12nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543920(CHEMBL4638896)
Affinity DataIC50: 13nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543921(CHEMBL4634285)
Affinity DataIC50: 13nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195170(2-chloro-N-((4-(morpholine-4-carbonyl)-1-(propylsu...)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457698(CHEMBL4213968)
Affinity DataIC50: 18nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457713(CHEMBL4218894)
Affinity DataIC50: 18nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195166(3-chloro-2,6-difluoro-N-((4-(morpholine-4-carbonyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50195178(2-chloro-6-fluoro-N-((4-(morpholine-4-carbonyl)-1-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of rat GlyT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543916(CHEMBL4639407)
Affinity DataIC50: 26nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457697(CHEMBL4215015)
Affinity DataIC50: 27nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457711(CHEMBL4211426)
Affinity DataIC50: 28nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457701(CHEMBL4207171)
Affinity DataIC50: 36nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543915(CHEMBL4644636)
Affinity DataIC50: 36nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50439754(CHEMBL2419440)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457705(CHEMBL4212425)
Affinity DataIC50: 78nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457709(CHEMBL4211293)
Affinity DataIC50: 79nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457690(CHEMBL4205726)
Affinity DataIC50: 82nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50543919(CHEMBL4645731)
Affinity DataIC50: 96nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457707(CHEMBL4210589)
Affinity DataIC50: 108nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50439750(CHEMBL2419441)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457708(CHEMBL4202824)
Affinity DataIC50: 161nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457701(CHEMBL4207171)
Affinity DataIC50: 172nMAssay Description:Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50457696(CHEMBL4214486)
Affinity DataIC50: 183nMAssay Description:Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 190nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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