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Report error Found 17 of affinity data for UniProtKB/TrEMBL: P27791
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 27nMAssay Description:Inhibition of cAMP-dependent kinase PKA(Protein kinase A) catalytic subunit at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM83205((E,2S,3R)-2-azanyloctadec-4-ene-1,3-diol | cid_528...)
Affinity DataIC50: 98nMAssay Description:Inhibition of cAMP-dependent kinase PKA(Protein kinase A) catalytic subunit at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2684(indolocarbazole deriv. 4f | 3-[3-(dimethylamino)pr...)
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2691(Bisindolyl deriv. 19 | 3-[1-(3-aminopropyl)-1H-ind...)
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
Affinity DataIC50: 1.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2687(methyl 3-{3-[4-(1H-indol-3-yl)-2,5-dioxo-2,5-dihyd...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
Affinity DataIC50: 2.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
Affinity DataIC50: 3.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50: 3.50E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
Affinity DataIC50: 4.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2688(3-(1H-indol-3-yl)-4-[1-(2-methoxyethyl)-1H-indol-3...)
Affinity DataIC50: 4.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
Affinity DataIC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
Affinity DataIC50: 6.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rat)
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2004
Entry Details
PubMed