Compile Data Set for Download or QSAR
Report error Found 1426 of affinity data for UniProtKB/TrEMBL: P21731
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM62356(US9422273, 12b)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
Go to US Patent

TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240745(US9422273, 12c)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240746(US9422273, 12d)
Affinity DataEC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM240747(US9422273, 12e)
Affinity DataEC50: >1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238316(US9394273, 6 | US9394273, 5)
Affinity DataEC50:  7.19E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataEC50:  4.83E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238319(US9394273, 10 | US9394273, 9 | US9394273, 8)
Affinity DataEC50:  100nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238319(US9394273, 10 | US9394273, 9 | US9394273, 8)
Affinity DataEC50:  108nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238322(US9394273, 12 | US9394273, 11)
Affinity DataEC50:  218nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataEC50: <10nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 20 | US9394273, 19)
Affinity DataEC50:  5.60E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
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TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238334(US9394273, 24 | US9394273, 23)
Affinity DataEC50:  2.45E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010072(CHEMBL318673 | [3-(5-oxabicyclo[2.2.1],3-formaldeh...)
Affinity DataKd:  1.20E+3nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010073(3-[2-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinoc...)
Affinity DataKd:  1nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010074(CHEMBL99041 | [3-(5-oxabicyclo[2.2.1],3-formaldehy...)
Affinity DataKd:  171nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010077(CHEMBL95867 | 4-[2-(5-oxabicyclo[2.2.1],3-formalde...)
Affinity DataKd:  21nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010076(CHEMBL99348 | {3-[2-(5-oxabicyclo[2.2.1],3-formald...)
Affinity DataKd:  1.07E+3nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010075(CHEMBL318426 | (5Z)-7-(5-oxabicyclo[2.2.1],3-forma...)
Affinity DataKd:  39nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50010078(CHEMBL95884 | [2-(5-oxabicyclo[2.2.1],3-formaldehy...)
Affinity DataKd:  6nMAssay Description:The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015847(CHEMBL312732 | 7-(3-{[2-(5-Cyclohexyl-pentanoylami...)
Affinity DataKd:  2.60nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015848(CHEMBL79287 | 7-{3-[(2-Heptanethioylamino-acetylam...)
Affinity DataKd:  12nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015849(CHEMBL81263 | 7-{3-[(2-Octanoylamino-acetylamino)-...)
Affinity DataKd:  50nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015850(CHEMBL79278 | 7-(3-{[2-(2-Phenylsulfanyl-acetylami...)
Affinity DataKd:  41nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015852(CHEMBL82146 | 7-{3-[(2-Nonanoylamino-acetylamino)-...)
Affinity DataKd:  8.30nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015851(CHEMBL83366 | 7-[3-({2-[2-(4-tert-Butyl-phenylsulf...)
Affinity DataKd:  4.20nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015853(CHEMBL310406 | 7-(3-{[2-(4-Cyclohexyl-butyrylamino...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50015854(CHEMBL312360 | 7-{3-[(2-Heptanethioylamino-thioace...)
Affinity DataKd:  26nMAssay Description:Binding affinity was determined from the inhibition of [3H]-SQ 29,548 binding to Thromboxane A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50016779(CHEMBL175303 | 7-(3-Propylsulfanylmethyl-7-oxa-bic...)
Affinity DataKd:  97nMAssay Description:Inhibition of specific binding of HSQ(5,6-di-3H-SQ 29,548) in washed plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50016780(CHEMBL175751 | 7-(3-But-3-enylsulfanylmethyl-7-oxa...)
Affinity DataKd:  49nMAssay Description:Inhibition of specific binding of HSQ(5,6-di-3H-SQ 29,548) in washed plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50016783(CHEMBL177949 | 7-(3-Allylsulfanylmethyl-7-oxa-bicy...)
Affinity DataKd:  76nMAssay Description:Inhibition of specific binding of HSQ(5,6-di-3H-SQ 29,548) in washed plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50072788((E)-7-{4-[4-((1R,2S)-2-Phenyl-cyclopropylcarbamoyl...)
Affinity DataKd:  63nMAssay Description:In vitro for antagonistic activity against thromboxane synthase receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50456020(CHEMBL2368531)
Affinity DataKd:  22nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047265(3-(2-{3-[4-(5-Hydroxy-pentylcarbamoyl)-oxazol-2-yl...)
Affinity DataKd:  20nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047266(3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  0.100nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047267(2-{3-[2-(3-Hydroxy-propyl)-benzyl]-7-oxa-bicyclo[2...)
Affinity DataKd:  112nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047268(3-(2-{3-[4-(4-Cyclohexylcarbamoyl-butylcarbamoyl)-...)
Affinity DataKd:  22nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047270(3-[2-(3-{4-[4-(4-Methoxy-phenyl)-butylcarbamoyl]-o...)
Affinity DataKd:  0.300nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047269(3-(2-{3-[4-(5,5,5-Trifluoro-pentylcarbamoyl)-oxazo...)
Affinity DataKd:  4.80nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047271(3-{2-[3-(4-tert-Butylcarbamoyl-oxazol-2-yl)-7-oxa-...)
Affinity DataKd:  19nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047272(3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-...)
Affinity DataKd:  36nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047273(2-{3-[2-(2-Carboxy-ethyl)-benzyl]-7-oxa-bicyclo[2....)
Affinity DataKd:  1nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047275(3-{2-[3-(4-Methylcarbamoyl-oxazol-2-yl)-7-oxa-bicy...)
Affinity DataKd:  45nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047274(BMS-180291 | 3-{2-[3-(4-Pentylcarbamoyl-oxazol-2-y...)
Affinity DataKd:  4nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047276(3-(2-{3-[4-(Methyl-pentyl-carbamoyl)-oxazol-2-yl]-...)
Affinity DataKd:  11nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047277((2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl...)
Affinity DataKd:  3.20nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047278(3-[2-(3-{4-[4-(4-Chloro-phenyl)-butylcarbamoyl]-ox...)
Affinity DataKd:  0.200nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047279(3-{2-[3-(4-Propylcarbamoyl-oxazol-2-yl)-7-oxa-bicy...)
Affinity DataKd:  10nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047281(2-{3-[2-(3-Methanesulfonylamino-3-oxo-propyl)-benz...)
Affinity DataKd:  1.60nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM50047280(3-[2-(3-{4-[4-(4-Hydroxy-phenyl)-butylcarbamoyl]-o...)
Affinity DataKd:  0.5nMAssay Description:Inhibitory binding activity against TXA2 receptor in human platelet membrane, using [3H]-SQ 29548 as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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