Compile Data Set for Download or QSAR
Report error Found 8 of affinity data for UniProtKB/TrEMBL: P21643
TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of TDO2 in rat liver homogenate assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289136(6-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289142(3-((E)-2-Pyridin-4-yl-vinyl)-1H-indole | CHEMBL166...)
Affinity DataKi:  30nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289138(3-((E)-2-Pyridin-3-yl-vinyl)-1H-indole | CHEMBL441...)
Affinity DataKi:  40nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289141(5-Fluoro-3-((E)-2-pyridin-4-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  40nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289140(5-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)
Affinity DataKi:  50nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTryptophan 2,3-dioxygenase(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50289139(3-((E)-2-Pyridin-2-yl-vinyl)-1H-indole | CHEMBL171...)
Affinity DataKi:  100nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article