Compile Data Set for Download or QSAR
Report error Found 1413 of affinity data for UniProtKB/TrEMBL: P21452
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50030211((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50030213((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50030212((S)-2-{2-[(2R,5S,8R)-5,8-Dibenzyl-2-(3-guanidino-p...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50030214((S)-2-{2-[(6R,9S,12R)-6,9-Dibenzyl-12-(3-guanidino...)
Affinity DataEC50: >5.00E+4nMAssay Description:Tested for the biological activity and selectivity against NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50259674((S)-3-amino-4-((S)-1-((R)-1-((S)-1-((R)-1-((R)-1-(...)
Affinity DataEC50:  78.1nMAssay Description:Displacement of [3H]SR48968 from human recombinant NK2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  10nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  208nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Phe270Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  48nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  291nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Phe270Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  1.90nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  48nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  2.70nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  3.10nMAssay Description:Compound was evaluated for Kd value against [125I]-NKA on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  26nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd: >1.00E+3nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  3.60nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  2.10nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50472911(CHEMBL407782 | MEN-11420)
Affinity DataKd:  4.40nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  34nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  1.30nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50404020(MEN-11558 | CHEMBL435324)
Affinity DataKd:  1.96E+3nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97485(US8470816, 458)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97486(US8470816, 464)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97489(US8470816, 632)
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97481(US8470816, 265)
Affinity DataIC50: 0.230nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97490(US8470816, 633)
Affinity DataIC50: 0.240nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97483(US8470816, 292)
Affinity DataIC50: 0.25nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97479(US8470816, 251a)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97487(US8470816, 623)
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97491(US8470816, 635)
Affinity DataIC50: 0.360nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50170968((S)-5-(3,4-Dichloro-phenyl)-1-(4,4-difluoro-cycloh...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human Neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97482(US8470816, 268)
Affinity DataIC50: 0.420nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataIC50: 0.440nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97472(US8470816, 18)
Affinity DataIC50: 0.450nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97488(US8470816, 629)
Affinity DataIC50: 0.550nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97480(US8470816, 252)
Affinity DataIC50: 0.560nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97478(US8470816, 91)
Affinity DataIC50: 0.790nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50409627(CHEMBL185572)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of human Neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity was determined against human NK2 receptor in CHO cells using [125I]neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97484(US8470816, 318)
Affinity DataIC50: 0.820nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50410049(CHEMBL434142)
Affinity DataIC50: 1nMAssay Description:Inhibition of human Neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97475(US8470816, 30)
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50410051(CHEMBL185182)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50410048(CHEMBL434548)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human Neurokinin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97476(US8470816, 31)
Affinity DataIC50: 1.70nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50001447(His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2(Neurok...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against human Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM97474(US8470816, 24)
Affinity DataIC50: 2nMpH: 7.5Assay Description:CHO cells expressing hNK2 receptor were cultured in a HAM-F12 medium containing 400 ug/mL geneticin, 100 U/mL penicillin, 100 ug/mL streptomycin and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM106976(US8592454, 66)
Affinity DataIC50: 2nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

Displayed 1 to 50 (of 1413 total ) | Next | Last >>
Jump to: