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TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367787(CHEMBL1202672)
Affinity DataIC50: 20nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719141(N-((5-(2-fluorophenyl)-1-((4-fluorophenyl)sulfonyl...)
Affinity DataIC50: 25nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719140(N-((1-((4-chlorophenyl)sulfonyl)-5-(2-fluorophenyl...)
Affinity DataIC50: 26nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367813(CHEMBL1202661)
Affinity DataIC50: 30nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719139( N-((1-((4-bromophenyl)sulfonyl)-5-(2-fluorophenyl...)
Affinity DataIC50: 36nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719148(N-((4-methoxy-1-(pyridin-3-ylsulfonyl)-5-(2,4,6-tr...)
Affinity DataIC50: 38nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM22893(CHEMBL512 | dimethyl[(5-{[(2-{[(E)-1-(methylamino)...)
Affinity DataIC50: 40nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719135(N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H...)
Affinity DataIC50: 42nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719137(N-((5-(2-fluorophenyl)-1-((4-methoxyphenyl)sulfony...)
Affinity DataIC50: 48nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367772(CHEMBL1202647)
Affinity DataIC50: 50nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367783(CHEMBL1202621)
Affinity DataIC50: 50nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719142(N-((5-(2-fluorophenyl)-1-((4-(trifluoromethoxy)phe...)
Affinity DataIC50: 51nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719143(N-((1-((4-chlorophenyl)sulfonyl)-5-(3-fluorophenyl...)
Affinity DataIC50: 60nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50008978(CHEMBL296482 | (+/-)-(2-Methyl-8-phenyl-7,8-dihydr...)
Affinity DataIC50: 64nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719149(N-((4-methoxy-1-((6-methoxypyridin-3-yl)sulfonyl)-...)
Affinity DataIC50: 64nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50008977((8-Benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-yl)-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719136(N-((5-(2-fluorophenyl)-1-tosyl-1H-pyrrol-3-yl)meth...)
Affinity DataIC50: 68nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719144(N-((5-(3-fluorophenyl)-1-((4-methoxyphenyl)sulfony...)
Affinity DataIC50: 76nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367787(CHEMBL1202672)
Affinity DataIC50: 80nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367772(CHEMBL1202647)
Affinity DataIC50: 80nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367790(CHEMBL1202681)
Affinity DataIC50: 80nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719145(N-((5-(2,4-difluorophenyl)-1-tosyl-1H-pyrrol-3-yl)...)
Affinity DataIC50: 82nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719146(N-((5-(2,4-difluorophenyl)-1-((4-methoxyphenyl)sul...)
Affinity DataIC50: 84nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719147(N-((5-(2,4-difluorophenyl)-4-methoxy-1-((6-methoxy...)
Affinity DataIC50: 88nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367801(CHEMBL1202667)
Affinity DataIC50: 90nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1(Human)
Hana Pharm

US Patent
LigandPNGBDBM719138(4-((2-(2-fluorophenyl)-4-(((methyl-d3)amino)methyl...)
Affinity DataIC50: 90nMAssay Description:60 ul of enzyme reaction solution (a test compound at a given concentration, 3 g of gastric mucosal microsomes, 3 mM of MgSO4, 5 mM of KCl, 40 mM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50008978(CHEMBL296482 | (+/-)-(2-Methyl-8-phenyl-7,8-dihydr...)
Affinity DataIC50: 92nMpH: 7.4Assay Description:Inhibition of purified H+/K+ ATPase at pH 7.4 as released inorganic phosphate from ATP using hog stomach gastric membrane vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367783(CHEMBL1202621)
Affinity DataIC50: 110nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367817(CHEMBL1202658)
Affinity DataIC50: 110nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367801(CHEMBL1202667)
Affinity DataIC50: 120nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367790(CHEMBL1202681)
Affinity DataIC50: 120nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367813(CHEMBL1202661)
Affinity DataIC50: 120nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367770(CHEMBL1202663)
Affinity DataIC50: 120nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50008969(CHEMBL293244 | (2-Methyl-8-phenethyl-imidazo[1,2-a...)
Affinity DataIC50: 130nMAssay Description:Inhibition of H+/K+ ATPase as reduced acid formation in rabbit gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367770(CHEMBL1202663)
Affinity DataIC50: 130nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367788(CHEMBL1202659)
Affinity DataIC50: 130nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367773(CHEMBL1202656)
Affinity DataIC50: 140nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367804(CHEMBL1202607)
Affinity DataIC50: 140nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367786(CHEMBL1202651)
Affinity DataIC50: 150nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367815(CHEMBL1202654)
Affinity DataIC50: 150nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367786(CHEMBL1202651)
Affinity DataIC50: 150nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367792(CHEMBL1202629)
Affinity DataIC50: 160nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367797(CHEMBL1202671)
Affinity DataIC50: 170nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367807(CHEMBL1202678)
Affinity DataIC50: 170nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367812(CHEMBL1202655)
Affinity DataIC50: 180nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367794(CHEMBL1202660)
Affinity DataIC50: 180nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367799(CHEMBL1202668)
Affinity DataIC50: 180nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367798(CHEMBL1202679)
Affinity DataIC50: 180nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367771(CHEMBL1202666)
Affinity DataIC50: 200nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetPotassium-transporting ATPase alpha chain 1/subunit beta(Human)
Ortho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50018887(CHEMBL20162 | 2-(1H-Benzoimidazole-2-sulfinylmethy...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against H+/K+ ATPase prepared from canine fundic mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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