Compile Data Set for Download or QSAR
Report error Found 5 of affinity data for UniProtKB/TrEMBL: P19332
TargetMicrotubule-associated protein tau(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340902((4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(2-fluo...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of tau protein phosphorylation at Ser396 in rat brain cells at 0.5 to 50 uM after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMicrotubule-associated protein tau(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50487729(CHEMBL454948)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetMicrotubule-associated protein tau(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50487730(CHEMBL508222)
Affinity DataEC50:  4.40E+3nMAssay Description:Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetMicrotubule-associated protein tau(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50313696(N-(6-chloro-7-fluoro-5-phenyl-1H-indazol-3-yl)buty...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Tau phosphorylation in rat cerebral cortex after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMicrotubule-associated protein tau(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Tau phosphorylation in rat cerebral cortex after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed