Compile Data Set for Download or QSAR
Report error Found 27 of affinity data for UniProtKB/TrEMBL: P19224
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50561654(CHEMBL4785914)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of UGT1A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 1.90E+4nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50511112(CHEMBL4567446)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of UGT1A6 in human liver microsomes incubated for 90 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM21363(12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...)
Affinity DataIC50: 2.30E+4nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 4.60E+4nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 6.70E+4nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 7.40E+4nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50241343(H-168/68 | 5-methoxy-2-(2-(4-methoxy-3,5-dimethylp...)
Affinity DataIC50: 1.85E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50027886(N-[(butylamino)carbonyl]-4-methylbenzenesulfonamid...)
Affinity DataIC50: 2.81E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of of UGT1A6 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM234401(Oleandomycin)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM8885(Testosterone, 1 | (1S,2R,10R,11S,14S,15S)-14-hydro...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM234400(Chlormethiazole)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50290811(CHEMBL1371 | 5-chlorobenzo[d]oxazol-2(3H)-one | 5-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50090677(CHEMBL1109 | 4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50048392(BUPROPION HYDROCHLORIDE | CHEMBL894 | 2-(tert-buty...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM21361((5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedi...)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM12342(2H-chromen-2-one | CHEMBL6466 | Coumarin)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50420191(ACETPHENETIDIN | Acetophenetidin | PHENACETIN)
Affinity DataIC50: 3.00E+5nMAssay Description:Refer to Fisher et al., Drug Metab. Dispos., 28:560-566.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataKi:  490nMAssay Description:Binding affinity to UGT1A6 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of AZT glucuronidation by human recombinant UGT1A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1-6(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50206509(CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probe...)
Affinity DataKi:  1.43E+6nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed