Compile Data Set for Download or QSAR
Report error Found 5 of affinity data for UniProtKB/TrEMBL: P18493
TargetPoly [ADP-ribose] polymerase 1(Bovine)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27709(CHEMBL401843 | 2-{3-[4-(4-fluorophenyl)-1,2,3,6-te...)
Affinity DataIC50: 16nMAssay Description:Inhibition of calf thymus PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Bovine)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27503(5-amino-1,2-dihydroisoquinolin-1-one | CHEMBL44624...)
Affinity DataIC50: 240nMAssay Description:Inhibition of calf thymus PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Bovine)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27503(5-amino-1,2-dihydroisoquinolin-1-one | CHEMBL44624...)
Affinity DataIC50: 250nMAssay Description:Inhibition of calf thymus PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Bovine)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM27500(Phenanthridone | 5H-Phenanthridin-6-one (PTD) | 5H...)
Affinity DataIC50: 300nMAssay Description:Inhibition of calf thymus ARTD1 assessed as incorporation of [Ade-U-14C]-NAD+ after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Bovine)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50446131(CHEMBL3108871)
Affinity DataIC50: 450nMAssay Description:Inhibition of bovine ARTD1 assessed as incorporation of [adenine-2,8-3H]NAD after 1 hr by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed