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TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370179(CHEMBL4163007)
Affinity DataIC50: 20nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520416(CHEMBL4553570)
Affinity DataIC50: 20nMAssay Description:Inhibition of acid sphingomyelinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638490(CHEMBL5288063)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370125(CHEMBL4176817)
Affinity DataIC50: 70nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370079(CHEMBL4167088)
Affinity DataIC50: 290nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370173(CHEMBL4161092)
Affinity DataIC50: 300nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632360(CHEMBL5434322)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370150(CHEMBL4172326)
Affinity DataIC50: 310nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520398(CHEMBL4551503)
Affinity DataIC50: 320nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520407(CHEMBL4464117)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370164(CHEMBL4169019)
Affinity DataIC50: 350nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520402(CHEMBL4517596)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human acid sphingomyelinase (His62 to Pro628 residues) using NBD-sphingomyelin as substrate after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520405(CHEMBL4464068)
Affinity DataIC50: 360nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638486(CHEMBL5559723)
Affinity DataIC50: 390nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370151(CHEMBL4175277)
Affinity DataIC50: 440nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638491(CHEMBL5556497)
Affinity DataIC50: 440nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632357(CHEMBL5409988)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 480nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 480nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638482(CHEMBL5542512)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632364(CHEMBL5413803)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632364(CHEMBL5413803)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638481(CHEMBL5566028)
Affinity DataIC50: 640nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632366(CHEMBL5401959)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632356(CHEMBL5416755)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638488(CHEMBL5559942)
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520406(CHEMBL4471880)
Affinity DataIC50: 880nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human acid sphingomyelinase (His62 to Pro628 residues) using NBD-sphingomyelin as substrate after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632368(CHEMBL5421810)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50407347(CHEMBL5273649)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of aSMase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370175(CHEMBL4167681)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370126(CHEMBL4167496)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632374(CHEMBL5395183)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638484(CHEMBL5542640)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520404(CHEMBL4449978)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50407249(CHEMBL5273927)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of aSMase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50407248(CHEMBL5271590)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of aSMase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50407247(CHEMBL5276301)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of aSMase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520399(CHEMBL4588641)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520397(CHEMBL4465034)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of human Huh7 cell derived acid sphingomyelinase using NBD-sphingomyelin as substrate after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520405(CHEMBL4464068)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human acid sphingomyelinase (His62 to Pro628 residues) using NBD-sphingomyelin as substrate after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50308980(6-O-Octylsulfonyl-D-glucose-2,4-bisphosphate | CHE...)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638483(CHEMBL5542655)
Affinity DataIC50: 2.71E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638489(CHEMBL5568173)
Affinity DataIC50: 3.03E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50370153(CHEMBL4175734)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of acid sphingomyelinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638492(CHEMBL5556653)
Affinity DataIC50: 3.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50632370(CHEMBL5440976)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human aSMase (62 to 628 residues) using HMU-PC as substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520398(CHEMBL4551503)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of recombinant human acid sphingomyelinase (His62 to Pro628 residues) using NBD-sphingomyelin as substrate after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520397(CHEMBL4465034)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of recombinant human acid sphingomyelinase (His62 to Pro628 residues) using NBD-sphingomyelin as substrate after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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