Compile Data Set for Download or QSAR
Report error Found 97 of affinity data for UniProtKB/TrEMBL: P16233
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.60nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human PL expressed in HEK293F cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 33nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 80.7nMAssay Description:Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hourMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 490nMAssay Description:Inhibition of Pancreatic lipase (unknown origin) using 4-MUO as fluorescent substrate preincubated for 3 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 780nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 806nMAssay Description:Compound was tested for inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367145(CHEMBL4173252)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367138(CHEMBL4160519)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 1.34E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.53E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50560416(CHEMBL4641560)
Affinity DataIC50: 1.63E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367133(CHEMBL4164998)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618931(CHEMBL5410259)
Affinity DataIC50: 1.86E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367134(CHEMBL4167341)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50625716(CHEMBL5416736)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367211(CHEMBL4165339)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50569167(CHEMBL4847734)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618932(CHEMBL1631675)
Affinity DataIC50: 2.13E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367212(CHEMBL4168413)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367214(CHEMBL4163899)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50022832(Rafoxanide)
Affinity DataIC50: 2.52E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50614084(CHEMBL4128298)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50232349(CHEMBL4102155)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human pancreatic lipase using 4-methylumbelliferyl oleate as substrate after 30 mins by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50179008(sanggenon C | CHEMBL204813)
Affinity DataIC50: 3.28E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50215413(CHEMBL360443)
Affinity DataIC50: 3.44E+3nMAssay Description:Compound was tested for inhibition of porcine pancreatic lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2018
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50569165(CHEMBL4856331)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618929(CHEMBL5423733)
Affinity DataIC50: 4.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50569166(CHEMBL4860907)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50569168(CHEMBL4847071)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of PTL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618927(CHEMBL5419885)
Affinity DataIC50: 5.99E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50625713(CHEMBL5425089)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618926(CHEMBL5413231)
Affinity DataIC50: 6.27E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618911(CHEMBL5405185)
Affinity DataIC50: 6.75E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367213(CHEMBL4175223)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367216(CHEMBL4176621)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367135(CHEMBL4160094)
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50232348(CHEMBL4077903)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human pancreatic lipase using 4-methylumbelliferyl oleate as substrate after 30 mins by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50625712(CHEMBL5407888)
Affinity DataIC50: 9.01E+3nMAssay Description:Inhibition of pancreatic lipase (unknown origin) by spectrophotometeric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367143(CHEMBL4168757)
Affinity DataIC50: 9.15E+3nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618915(CHEMBL5439220)
Affinity DataIC50: 9.24E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618910(CHEMBL5402667)
Affinity DataIC50: 9.96E+3nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618925(CHEMBL5399755)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50138734(3-(3-Benzyloxy-phenyl)-5-ethoxy-3H-[1,3,4]oxadiazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618919(CHEMBL5420710)
Affinity DataIC50: 1.05E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618918(CHEMBL5430137)
Affinity DataIC50: 1.10E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50618912(CHEMBL5436175)
Affinity DataIC50: 1.14E+4nMAssay Description:Negative allosteric modulator activity at human Pancreatic lipase using DDAO-ol as fluorescent substrate preincubated for 3 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50367136(CHEMBL4172103)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human pancreatic lipase using emulsified olive oil as substrate pretreated with substrate for 5 mins followed by enzyme addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
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