TargetSodium channel protein type 1/2/3/4/5/8/9/10/11 subunit alpha(Rat)
Tohoku University
Curated by ChEMBL
Tohoku University
Curated by ChEMBL
Affinity DataKd: 1.80nMAssay Description:Displacement of [3H]saxitoxin from NaV in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+5nMAssay Description:Inhibition of rat Nav1.5 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair
Affinity DataIC50: 2.87E+5nMAssay Description:Inhibition of rat Nav1.5 channel expressed in Xenopus oocytes by whole cell voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 8.71E+5nMAssay Description:Inhibition of rat Nav1.5 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two...More data for this Ligand-Target Pair

3D Structure (crystal)

