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TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50089691(CHEMBL3577425)
Affinity DataIC50: 1nMAssay Description:Inhibition of CBP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144342(3-((1R,3S)-3-Amino-cyclopentyl)-2-[1-(3,3-dimethyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144336(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(3-methyl-b...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144333(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(4-methyl-p...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120796(US8710232, 33)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144337(3-(6-Amino-pyridin-3-yl)-2-[1-(4-methyl-pentyl)-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120790(US8710232, 17)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120787(US8710232, 13)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120788(US8710232, 15)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120786(US8710232, 12)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120782(US8710232, 7)
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144316(3-(6-Amino-5-methyl-pyridin-3-yl)-2-(1H-imidazol-4...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120791(US8710232, 18)
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120785(US8710232, 10)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120781(US8710232, 1)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120789(US8710232, 16)
Affinity DataIC50: 38nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120797(US8710232, 37)
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50135933(3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-prop...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144325(3-((1R,3S)-3-Amino-cyclopentyl)-2-(1-ethyl-1H-imid...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144317(6-Amino-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-he...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50089685(CHEMBL3577333)
Affinity DataIC50: 190nMAssay Description:Inhibition of CBP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50233004(2-(3-carbamimidamidopropylidene)butanedioic acid |...)
Affinity DataIC50: 360nMAssay Description:Inhibition of carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120784(US8710232, 9)
Affinity DataIC50: 439nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144320(6-Amino-2-(1H-imidazol-4-yl)-5,5-dimethyl-hexanoic...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120795(US8710232, 31)
Affinity DataIC50: 870nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120793(US8710232, 27)
Affinity DataIC50: 1.11E+3nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120783(US8710232, 8)
Affinity DataIC50: 1.13E+3nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120794(US8710232, 28)
Affinity DataIC50: 1.44E+3nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144322(6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50144334(6-Amino-2-(1H-imidazol-4-yl)-hexanoic acid | CHEMB...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM120792(US8710232, 25)
Affinity DataIC50: 1.05E+4nMpH: 7.4 T: 2°CAssay Description:The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50530229(CHEMBL4460840)
Affinity DataKi:  0.120nMAssay Description:Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50530229(CHEMBL4460840)
Affinity DataKi:  0.120nMAssay Description:Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305348((S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-...)
Affinity DataKi:  27nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305346((S)-2-(2-aminoethoxy)-3-(1-phenyl-1H-imidazol-4-yl...)
Affinity DataKi:  27nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305347((S)-2-(2-aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H...)
Affinity DataKi:  49nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50226610((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Affinity DataKi:  206nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305345((S)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...)
Affinity DataKi:  238nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305352((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-phenyl-1H-i...)
Affinity DataKi:  240nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305351((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-(pyridin-2-...)
Affinity DataKi:  265nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305349((+/-)-2-(2-aminoethoxy)-3-(1-butyl-1H-imidazol-4-y...)
Affinity DataKi:  360nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50270378(trans-1,1,3,3-tetraisopropyl-2-(3-(4-nitrophenyl)-...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of human carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50296412(DL-guanidinoethylmercaptosuccinic acid | CHEMBL560...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50226606((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50296414(N-(3-chlorophenyl)-4-((5-(3-methoxybenzylthio)-1,3...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50305350((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...)
Affinity DataKi:  2.72E+3nMAssay Description:Inhibition of human pancreatic carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50270380(trans-1,1,3,3-tetraisopropyl-2-((2S,3S)-3-(4-metho...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50270379(trans-1,1,3,3-tetraisopropyl-2-((2S,3S)-3-(4-(trif...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of human carboxypeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxypeptidase B(Human)
Institute For Infection Research

Curated by ChEMBL
LigandPNGBDBM50296413(N-benzyl-N-(4-phenylthiazol-2-yl)cyclopropanecarbo...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human recombinant carboxypeptidase B expressed in Pichia pastoris systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
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