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TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.93E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740623(US20250154153, Compound 1218-40)
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740621(US20250154153, Compound 1218-20S)
Affinity DataIC50: 0.141nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740619(US20250154153, Compound 1218-39)
Affinity DataIC50: 0.191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740628(US20250154153, Compound 1109-51)
Affinity DataIC50: 0.191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740622(US20250154153, Compound 1218-20R)
Affinity DataIC50: 0.209nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740620(US20250154153, Compound 1218-20)
Affinity DataIC50: 0.219nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740622(US20250154153, Compound 1218-20R)
Affinity DataIC50: 0.269nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740621(US20250154153, Compound 1218-20S)
Affinity DataIC50: 0.282nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740629(US20250154153, Compound 1109-52)
Affinity DataIC50: 0.282nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740620(US20250154153, Compound 1218-20)
Affinity DataIC50: 0.288nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740632(US20250154153, Compound 1109-55S)
Affinity DataIC50: 0.288nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740619(US20250154153, Compound 1218-39)
Affinity DataIC50: 0.398nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740627(US20250154153, Compound 1109-14)
Affinity DataIC50: 0.427nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740625(US20250154153, Compound 1218-4B)
Affinity DataIC50: 0.525nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740626(US20250154153, Compound 1109-15)
Affinity DataIC50: 0.603nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740624(US20250154153, Compound 1218-4A)
Affinity DataIC50: 0.617nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740626(US20250154153, Compound 1109-15)
Affinity DataIC50: 0.708nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740632(US20250154153, Compound 1109-55S)
Affinity DataIC50: 0.724nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740623(US20250154153, Compound 1218-40)
Affinity DataIC50: 0.794nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740630(US20250154153, Compound 1109-52S)
Affinity DataIC50: 1.07nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740628(US20250154153, Compound 1109-51)
Affinity DataIC50: 1.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601469(CHEMBL5172164)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740625(US20250154153, Compound 1218-4B)
Affinity DataIC50: 1.41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740629(US20250154153, Compound 1109-52)
Affinity DataIC50: 1.51nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740624(US20250154153, Compound 1218-4A)
Affinity DataIC50: 1.82nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740631(US20250154153, Compound 1109-55)
Affinity DataIC50: 1.91nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740630(US20250154153, Compound 1109-52S)
Affinity DataIC50: 2.14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740627(US20250154153, Compound 1109-14)
Affinity DataIC50: 2.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161301(2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055374([3-Aminooxalyl-1-(2-benzyl-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161305((3-Aminooxalyl-1-cyclohexylmethyl-2-methyl-2,3-dih...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50601472(CHEMBL5208632)
Affinity DataIC50: 5nMAssay Description:Inhibition of human group IIA phospholipase A2 preincubated with compound for 10 mins followed by enzyme addition and measured after 30 mins by PC/DO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM740631(US20250154153, Compound 1109-55)
Affinity DataIC50: 5.37nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
Go to US Patent

TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055379((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-cyclopropyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055401((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-ethyl-1H-in...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055378([3-Aminooxalyl-1-(2,6-dichloro-benzyl)-2-methyl-1H...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055401((3-Aminooxalyl-1-biphenyl-2-ylmethyl-2-ethyl-1H-in...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055387((R)-2-(3-Aminooxalyl-1-benzyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161293((3-Aminooxalyl-1-benzyl-2-methyl-1,6,7,8-tetrahydr...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055371((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 30 mins by automatic plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055366(Varespladib sodium | (3-Aminooxalyl-1-benzyl-2-eth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055367([3-Aminooxalyl-1-(3-chloro-benzyl)-2-ethyl-1H-indo...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50055366(Varespladib sodium | (3-Aminooxalyl-1-benzyl-2-eth...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50161299((3-Aminooxalyl-1-benzyl-2-ethyl-1,6,7,8-tetrahydro...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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