Compile Data Set for Download or QSAR
Report error Found 29 of affinity data for UniProtKB/TrEMBL: P14099
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059037(2-benzyl-5-methyl-(6aR,9aS)-1,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059037(2-benzyl-5-methyl-(6aR,9aS)-1,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Phosphodiesterase 2 from bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059026(5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059044((6aR,9aS)-2-(Biphenylmethyl)-5,6a,7,8,9,9a-hexahyd...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100673(methyl 2-(4-aminophenyl)-4-(4-bromo-3,5-dimethoxyp...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059061((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-5-methyl-2-(phen...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100674(methyl 2-(4-aminophenyl)-4-(3,5-dimethoxy-4-methyl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50040375(1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of phosphodiesterase 2 at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL77971 | CHEMBL553371 | methyl 2-(4-aminophen...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100670(methyl 2-(4-aminophenyl)-1-oxo-7-(4-pyridylmethoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL77971 | CHEMBL553371 | methyl 2-(4-aminophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100656(2-(4-Amino-phenyl)-7-benzyloxy-1-oxo-4-(3,4,5-trim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50100659(methyl 2-(4-aminophenyl)-1-oxo-7-(3-pyridylmethoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059063(1-{4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-6-chlor...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061899(2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Phosphodiesterase 2 from bovine adrenal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059062(2-hexyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059052(5'-Methyl-2'-(cyclopentylmethyl)spiro[cyclopentane...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059028(2,5-dimethyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclopent...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059054(5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50059024((6aR,9aS)-2-(Cyclopentylmethyl)-5,6a,7,8,9,9a-hexa...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50130021(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyridin-2...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50242771(8-Benzyl-2-methyl-4-(N-methylamino)pyrazolo[1,5-a]...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of bovine aorta PDE2 in presence of cGMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50130016(8-(2-Hydroxy-ethylamino)-2-(2-methyl-pyridin-4-ylm...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50130017(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50130026(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrimidin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50130024(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(2-pyridin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bovine)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50048241((3S,4S)-3-Acetyl-4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of bovine Phosphodiesterase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed