Compile Data Set for Download or QSAR
Report error Found 27 of affinity data for UniProtKB/TrEMBL: P12276
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50362887(AVICULARIN)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318454(Diallyl trisulfide | diallyltrisulfane | CHEMBL123...)
Affinity DataIC50: 8.37E+3nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318454(Diallyl trisulfide | diallyltrisulfane | CHEMBL123...)
Affinity DataIC50: 8.37E+3nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM240798(Ginkgolic acid C17:2 (2))
Affinity DataIC50: 9.20E+3nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50259930(6-[10'(Z)-heptade-cenyljsalicylic acid | 6-(10'Z-h...)
Affinity DataIC50: 1.05E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50349517(CHEMBL1808693)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of chicken FAS by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50009248(CHEMBL45627 | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)...)
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50615544(CHEMBL5283434)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50615540(CHEMBL5271377)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50615541(CHEMBL5266900)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50615542(CHEMBL5269517)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50615543(CHEMBL5274276)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394659(CHEMBL2165410)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50242188(6-{8(Z)-pentadecenyl}salicylic acid | Anacardic ac...)
Affinity DataIC50: 1.71E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394660(CHEMBL2165409)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of chicken liver FASN after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of chicken liver FASN using acetyl-CoA, malonyl-CoA and NADPH as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50148911(3beta-hydroxyurs-12-en-28-oic acid | (3beta)-3-hyd...)
Affinity DataIC50: 5.93E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 6.25E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50153015((-)epicatechingallate | (2R,3R)-2-(3,4-dihydroxyph...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394663(CHEMBL2165267)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318453(3-Allyldisulfanyl-propene | Diallyl disulfide | CH...)
Affinity DataIC50: 1.45E+5nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetFatty acid synthase(Chicken)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM233038(Dimethyl disulfide)
Affinity DataIC50: 2.21E+6nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed