Compile Data Set for Download or QSAR
Report error Found 3346 of affinity data for UniProtKB/TrEMBL: P11511
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9991((2S,6S,15S)-6-hydroxy-2-(methoxymethyl)-15-methylt...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8938(dihydronaphthalene derivative | 7-(1H-Imidazol-5-y...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8939(4-({9-methoxy-2-methyl-3-oxatricyclo[5.4.0.0^{2,4}...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8947(6,7-Dihydroxy-2-(1H-imidazol-5-ylmethyl)-3,4-dihyd...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8948(1-{[4-(3-methoxyphenyl)phenyl]methyl}-1H-imidazole...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8949(3-[4-(1H-imidazol-1-ylmethyl)phenyl]phenol | methy...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8950(2-[4-(1H-imidazol-1-ylmethyl)phenyl]benzene-1,4-di...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8952(4-[4-(1H-imidazol-1-ylmethyl)phenyl]benzene-1,2,3-...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8954(1-{[4-(2,5-dimethoxyphenyl)phenyl]methyl}-1H-imida...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8955(1-[(3,4-dimethoxy-1,1-biphenyl-4-yl)methyl]-1H-imi...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8957(1-{[4-(3,4,5-trimethoxyphenyl)phenyl]methyl}-1H-im...)
Affinity DataAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9466(4-(9-Phenyl-9H-fluoren-9-yl)-4H-1,2,4-triazole | F...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9467(1-(9-Phenyl-9H-fluoren-9-yl)-1H-1,2,3-triazole | F...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9474(4-[2-(1H-Imidazol-1-yl)ethoxy]-7-methoxy-2H-chrome...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9479(7-(1H-1,2,4-Triazol-1-ylmethyl)-2H-chromen-2-one |...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9480(7-[2-(1H-Imidazol-1-yl)ethoxy]-2H-chromen-2-one | ...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9481(8-(1H-Imidazol-1-ylmethyl)-7-methoxy-2H-chromen-2-...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9484(7-methoxy-4-(pyridin-4-yl)-2H-chromen-2-one | Coum...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM24302((2-methoxy-5-{[4-methoxy-3-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM24303((2-methoxy-4-{[3-methoxy-4-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of aromatase (unknown origin) transfected in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50539776(CHEMBL4639677)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50539777(CHEMBL4632445)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337121(2-chloro-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triaz...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337123(4-(((6-cyano-4'-methoxybiphenyl-3-yl)(4H-1,2,4-tri...)
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337122(2-bromo-4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazo...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 0.0300nMAssay Description:In vitro inhibition of estrogen production in hamster ovarian tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337118(5'-((4-bromobenzyl)(4H-1,2,4-triazol-4-yl)amino)-2...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50592781(CHEMBL5203413)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50123025(CHEMBL3623231)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337117(5'-(benzyl(4H-1,2,4-triazol-4-yl)amino)-2'-cyanobi...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307918(2-(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM10007(4-[6-Methoxybenzofuran-2-yl)-1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM10016(4-{[(4-bromophenyl)methyl](4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of aromatase in human placental microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307884(3-CHLORO-2'-CYANO-5'-(1H-1,2,4-TRIAZOL-1-YLMETHYL)...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50525257(CHEMBL4520995)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human placental microsome aromatase using [1beta,2beta3H]androstenedione as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337120(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307901(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chloro-4'-hyd...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione as substrate incubated for 1 hr and measured by BCA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM24341(4-{[(4-chloro-3-hydroxyphenyl)methyl](4H-1,2,4-tri...)
Affinity DataIC50: 0.180nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50123026(CHEMBL3623232)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells using [1beta-3H] androstenedione as substrate assessed as tritiated H2O release after 1 hr by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307899(5-((1H-1,2,4-triazol-1-yl)methyl)biphenyl-2-carbon...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307900(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-hydroxybiphen...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50525260(CHEMBL4465348)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50337119(4-(((6-cyanobiphenyl-3-yl)(4H-1,2,4-triazol-4-yl)a...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307902(5-((1H-1,2,4-triazol-1-yl)methyl)-4'-chloro-3'-hyd...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50307919(5-((1H-1,2,4-triazol-1-yl)methyl)-3'-chlorobipheny...)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of aromatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM50121079(CHEMBL3622064)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
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