Compile Data Set for Download or QSAR
Report error Found 668 for UniProtKB: P0C6U8
TargetReplicase polyprotein 1a(SARS-CoV)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50002861(3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid | Dayp...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to 15N-labelled His6-tagged SARS-CoV Mac3 (527 to 652 residue) expressed in Escherichia coli Rosetta assessed as chemical shift pert...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM22971(Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to 15N-labelled His6-tagged SARS-CoV Mac3 (527 to 652 residue) expressed in Escherichia coli Rosetta assessed as chemical shift pert...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM60986(cid_16129778 | MLS001335996 | SMR000857330 | TANNI...)
Affinity DataEC50:  8.31E+3nMAssay Description:Inhibition of SARS-CoV 3CLproMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM31524(Naphthalene and Benzamide Derivative, 25 | 5-amino...)
Affinity DataKd:  2.70E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496476(SARS-CoV-2 PLpro Inhibitor, 5 | US20240166598, Com...)
Affinity DataKd:  1.60E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676187(US20240166598, Compound ZN-2-181)
Affinity DataKd:  4.70E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676188(US20240166598, Compound ZN-2-182)
Affinity DataKd:  3.26E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676189(US20240166598, Compound ZN-2-183)
Affinity DataKd:  3.11E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496522(SARS-CoV-2 PLpro Inhibitor, 6 | US20240166598, Com...)
Affinity DataKd:  1.03E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496522(SARS-CoV-2 PLpro Inhibitor, 6 | US20240166598, Com...)
Affinity DataKd:  1.80E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496553(SARS-CoV-2 PLpro Inhibitor, 7 | US20240166598, Com...)
Affinity DataKd:  3.10E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496554(SARS-CoV-2 PLpro Inhibitor, 8 | US20240166598, Com...)
Affinity DataKd:  5.40E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496555(SARS-CoV-2 PLpro Inhibitor, 9 | US20240166598, Com...)
Affinity DataKd:  1.30E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496557(SARS-CoV-2 PLpro Inhibitor, 10 | US20240166598, Co...)
Affinity DataKd:  5.60E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496558(SARS-CoV-2 PLpro Inhibitor, 11 | US20240166598, Co...)
Affinity DataKd:  3.40E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496585(SARS-CoV-2 PLpro Inhibitor, 12 | US20240166598, Co...)
Affinity DataKd:  2.80E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496586(SARS-CoV-2 PLpro Inhibitor, 13 | US20240166598, Co...)
Affinity DataKd:  2.65E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496607(SARS-CoV-2 PLpro Inhibitor, 14 | US20240166598, Co...)
Affinity DataKd:  6.00E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496685(SARS-CoV-2 PLpro Inhibitor, 15 | US20240166598, Co...)
Affinity DataKd:  8.16E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496722(SARS-CoV-2 PLpro Inhibitor, 19 | US20240166598, Co...)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496768(SARS-CoV-2 PLpro Inhibitor, 20 | US20240166598, Co...)
Affinity DataKd:  2.00E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496791(SARS-CoV-2 PLpro Inhibitor, 21 | US20240166598, Co...)
Affinity DataKd:  4.54E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496792(SARS-CoV-2 PLpro Inhibitor, 22 | US20240166598, Co...)
Affinity DataKd:  5.46E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496793(SARS-CoV-2 PLpro Inhibitor, 23 | US20240166598, Co...)
Affinity DataKd:  8.30E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496794(SARS-CoV-2 PLpro Inhibitor, 24 | US20240166598, Co...)
Affinity DataKd:  2.96E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496796(SARS-CoV-2 PLpro Inhibitor, 26 | US20240166598, Co...)
Affinity DataKd:  8.83E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496798(SARS-CoV-2 PLpro Inhibitor, 28 | US20240166598, Co...)
Affinity DataKd:  4.32E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496799(SARS-CoV-2 PLpro Inhibitor, 29 | US20240166598, Co...)
Affinity DataKd:  4.34E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496800(SARS-CoV-2 PLpro Inhibitor, 30 | US20240166598, Co...)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496801(SARS-CoV-2 PLpro Inhibitor, 31 | US20240166598, Co...)
Affinity DataKd:  1.93E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496802(SARS-CoV-2 PLpro Inhibitor, 32 | US20240166598, Co...)
Affinity DataKd:  2.46E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496803(SARS-CoV-2 PLpro Inhibitor, 33 | US20240166598, Co...)
Affinity DataKd:  2.06E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496804(SARS-CoV-2 PLpro Inhibitor, 34 | US20240166598, Co...)
Affinity DataKd:  4.19E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676218(US20240166598, Compound ZN-3-13)
Affinity DataKd:  3.91E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676219(US20240166598, Compound ZN-3-19)
Affinity DataKd:  1.84E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676220(US20240166598, Compound DY2-97)
Affinity DataKd:  7.22E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676221(US20240166598, Compound ZN-3-61)
Affinity DataKd:  2.82E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676222(US20240166598, Compound ZN-3-32)
Affinity DataKd:  2.40E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676223(US20240166598, Compound ZN-3-33)
Affinity DataKd:  5.46E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496812(SARS-CoV-2 PLpro Inhibitor, 42 | US20240166598, Co...)
Affinity DataKd:  1.86E+5nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676225(US20240166598, Compound DY2-116)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676226(US20240166598, Compound XDY2-62)
Affinity DataKd:  6.70E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676227(US20240166598, Compound XDY2-58)
Affinity DataKd:  2.97E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676228(US20240166598, Compound YF4-134)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676229(US20240166598, Compound YF4-136)
Affinity DataKd:  3.03E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496819(SARS-CoV-2 PLpro Inhibitor, 49 | US20240166598, Co...)
Affinity DataKd: >1.00E+6nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676232(US20240166598, Compound DY2-125)
Affinity DataKd:  3.22E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/26/2024
Entry Details
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TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM496822(SARS-CoV-2 PLpro Inhibitor, 52 | US20240166598, Co...)
Affinity DataKd:  1.88E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676234(US20240166598, Compound DY-3-59)
Affinity DataKd:  1.83E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandPNGBDBM676235(US20240166598, Compound DY-3-66)
Affinity DataKd:  1.41E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent

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