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Report error Found 27 of affinity data for UniProtKB/TrEMBL: P0A031
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus FTsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50589185(CHEMBL5199894)
Affinity DataKd:  600nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50402381(CHEMBL2207296)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605151(CHEMBL5188114)
Affinity DataKd:  2.38E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605149(CHEMBL5200927)
Affinity DataKd:  2.49E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50399003(CHEMBL2180486)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605150(CHEMBL5174791)
Affinity DataKd:  3.84E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50605152(CHEMBL5186593)
Affinity DataKd:  3.86E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50402380(CHEMBL2207300)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50201769(CHEMBL3416823)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50201769(CHEMBL3416823)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 4.40E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
Go to US Patent

TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50608376(CHEMBL3416822)
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50439495(CHEMBL2418095)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50608375(CHEMBL3416821)
Affinity DataIC50: 7.72E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 7.74E+4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM186046(US9169182, J24)
Affinity DataIC50: 8.80E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
Go to US Patent

TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50608374(CHEMBL3416820)
Affinity DataIC50: 3.17E+5nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandPNGBDBM50201768(CHEMBL2413354)
Affinity DataIC50: 3.17E+5nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed