Compile Data Set for Download or QSAR
Report error Found 9 of affinity data for UniProtKB/TrEMBL: P09810
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243022((S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataEC50:  63nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243619((S) -2-amino-3-[4-(2-amino-6-[2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  70nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  48nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243617((S)-2-Amino-3-(4-{2-amino-6-[2,2,2-trifluoro-1-(3'...)
Affinity DataEC50:  56nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243024((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataEC50:  510nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243023((S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50019143(CHEMBL511275 | US10683309, Example LP533401)
Affinity DataIC50: 400nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetTryptophan 5-hydroxylase 1(Rat)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50019142(CHEMBL3288777)
Affinity DataIC50: 6.22E+3nMAssay Description:Inhibition of TPH-1-mediated serotonin biosynthesis in rat RBL2H3 cells after 48 hrs by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed